| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4336043 | B | Agonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as increase in calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA4336044 | B | Agonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as increase in calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4336045 | B | Agonist activity at human AChR alpha7 transfected in rat GH3 cells assessed as increase in calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4336046 | B | Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4336047 | B | Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4336048 | B | Antagonist activity at human AChR alpha7 transfected in rat GH3 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4336049 | B | Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx at 10 to 100 uM incubated for 1 hr by fluo-4 dye based assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4336051 | B | Selectivity index, ratio of IC50 for human AChR alpha4beta2 transfected in human HEK293 cells to IC50 for human AChR alpha3beta4 transfected in human HEK293 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4336052 | B | Selectivity index, ratio of IC50 for human AChR alpha7 transfected in rat GH3 cells to IC50 for human AChR alpha3beta4 transfected in human HEK293 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4336053 | B | Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx at 10 to 100 uM incubated for 1 hr by fluo-4 dye based assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4336054 | B | Antagonist activity at human AChR alpha7 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx at 10 to 100 uM incubated for 1 hr by fluo-4 dye based assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature |
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