# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4365247 | B | Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 38 | cell-based format | Scientific Literature | ||
2. | ALA4365248 | A | Antagonist activity at rat alpha6alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 38 | cell-based format | Scientific Literature | ||
3. | ALA4365249 | B | Selectivity ratio of IC50 for rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes to IC50 for rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes | Rattus norvegicus | 41 | cell-based format | Scientific Literature | ||
4. | ALA4365266 | B | Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay relative to PeIA logIC50 | Rattus norvegicus | 25 | cell-based format | Scientific Literature | ||
5. | ALA4365267 | A | Antagonist activity at rat alpha6alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay relative to PeIA logIC50 | Rattus norvegicus | 25 | cell-based format | Scientific Literature | ||
6. | ALA4811702 | B | Inhibition of human alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measured after 5 min by two-electrode voltage-clamp method | Homo sapiens | 53 | cell-based format | Scientific Literature | ||
7. | ALA4811703 | B | Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measured after 5 min by two-electrode voltage-clamp method | Rattus norvegicus | 56 | cell-based format | Scientific Literature | ||
8. | ALA4811704 | B | Inhibition of human alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measured after 5 min by two-electrode voltage-clamp relative to peIA | Homo sapiens | 52 | cell-based format | Scientific Literature | ||
9. | ALA4811705 | B | Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measured after 5 min by two-electrode voltage-clamp method relative to peIA | Rattus norvegicus | 52 | cell-based format | Scientific Literature | ||
10. | ALA4811706 | B | Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by measuring fold change measured after 5 min by two-electrode voltage-clamp method relative to peIA | Rattus norvegicus | 34 | cell-based format | Scientific Literature | ||
11. | ALA4811707 | B | Inhibition of human alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by measuring fold change measured after 5 min by two-electrode voltage-clamp method relative to peIA | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
12. | ALA4811710 | B | Inhibition of rat alpha6beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measured after 5 min by two-electrode voltage-clamp method | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
13. | ALA4811711 | B | Selectivity ratio of IC50 for rat alpha6beta4 nAChR to IC50 for rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes | Rattus norvegicus | 5 | cell-based format | Scientific Literature |