# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4386953 | B | Inhibition of tyrosinase in mouse B16F0 cells using L-DOPA as substrate by UV-Visible spectrophotometric analysis | Mus musculus | 2 | ALA4385634 | cell-based format | Scientific Literature | |
2. | ALA4386954 | B | Inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate preincubated for 10 mins followed by substrate addition by UV-Visible spectrophotometric analysis | Agaricus bisporus | 2 | ALA4385634 | single protein format | Scientific Literature | |
3. | ALA4386955 | B | Inhibition of tyrosinase in mouse B16F0 cells at 10 uM using L-DOPA as substrate by UV-Visible spectrophotometric analysis relative to control | Mus musculus | 2 | ALA4385634 | cell-based format | Scientific Literature | |
4. | ALA4386956 | B | Inhibition of tyrosinase in mouse B16F0 cells at 100 uM using L-DOPA as substrate by UV-Visible spectrophotometric analysis relative to control | Mus musculus | 2 | ALA4385634 | cell-based format | Scientific Literature | |
5. | ALA4386957 | B | Potency index, ratio of compound effect to KA effect for inhibition of tyrosinase in mouse B16F0 cells at 10 uM using L-DOPA as substrate | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
6. | ALA4386958 | B | Potency index, ratio of IC50 for KA to IC50 for test compound for inhibition of tyrosinase in mouse B16F0 cells using L-DOPA as substrate by UV-Visible spectrophotometric analysis | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
7. | ALA4386959 | A | Cytotoxicity against mouse B16F0 cells incubated for 24 hrs by MTT assay | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
8. | ALA4386960 | B | Inhibition of tyrosinase in mouse B16F0 cells assessed as reduction in melanin production incubated for 24 hrs by spectrophotometric analysis | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
9. | ALA4386961 | B | Potency index, ratio of IC50 for KA to IC50 for test compound for inhibition of tyrosinase in mouse B16F0 cells assessed as reduction in melanin production incubated for 24 hrs by spectrophotometric analysis | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
10. | ALA4386962 | B | Inhibition of intracellular tyrosinase in mouse B16F0 cells at 1 uM using L-DOPA as substrate preincubated with compound followed by substrate addition and measured after 20 mins by UV-Visible spectrophotometric analysis relative to control | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
11. | ALA4386963 | B | Inhibition of intracellular tyrosinase in mouse B16F0 cells at 5 uM using L-DOPA as substrate preincubated with compound followed by substrate addition and measured after 20 mins by UV-Visible spectrophotometric analysis relative to control | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
12. | ALA4386964 | B | Inhibition of intracellular tyrosinase in mouse B16F0 cells at 10 uM using L-DOPA as substrate preincubated with compound followed by substrate addition and measured after 20 mins by UV-Visible spectrophotometric analysis relative to control | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
13. | ALA4386965 | B | Inhibition of intracellular tyrosinase in mouse B16F0 cells at 25 uM using L-DOPA as substrate preincubated with compound followed by substrate addition and measured after 20 mins by UV-Visible spectrophotometric analysis relative to control | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
14. | ALA4386966 | B | Inhibition of intracellular tyrosinase in mouse B16F0 cells at 50 uM using L-DOPA as substrate preincubated with compound followed by substrate addition and measured after 20 mins by UV-Visible spectrophotometric analysis relative to control | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
15. | ALA4386967 | B | Inhibition of intracellular tyrosinase in mouse B16F0 cells at 100 uM using L-DOPA as substrate preincubated with compound followed by substrate addition and measured after 20 mins by UV-Visible spectrophotometric analysis relative to control | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
16. | ALA4386974 | B | Potency index, ratio of compound effect to KA effect for inhibition of intracellular tyrosinase in mouse B16F0 cells using L-DOPA as substrate preincubated with compound followed by substrate addition and measured after 20 mins by UV-Visible spectrophotometric analysis | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
17. | ALA4386975 | B | Inhibition of intracellular tyrosinase in mouse B16F0 cells using L-DOPA as substrate preincubated with compound followed by substrate addition and measured after 20 mins by UV-Visible spectrophotometric analysis relative to control | Mus musculus | 1 | ALA4385634 | cell-based format | Scientific Literature | |
18. | ALA4386976 | B | Potency index, ratio of IC50 for KA to IC50 for test compound for inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate preincubated for 10 mins followed by substrate addition by UV-Visible spectrophotometric analysis | Agaricus bisporus | 1 | ALA4385634 | single protein format | Scientific Literature |