# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4432298 | B | Inhibition of recombinant Trypanosoma cruzi triosephosphate isomerase assessed as reduction of DHAP at 200 uM after 2 hrs by measuring NADH consumption by alpha-glycerolphosphate dehydrogenase coupled assay | Trypanosoma cruzi | 9 | ALA4431335 | single protein format | Scientific Literature | |
2. | ALA4432299 | P | Solubility of the compound in DMSO at 200 uM | 13 | ALA4431335 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4432300 | B | Inhibition of recombinant Trypanosoma cruzi triosephosphate isomerase assessed as reduction of DHAP after 2 hrs by measuring NADH consumption by alpha-glycerolphosphate dehydrogenase coupled assay | Trypanosoma cruzi | 3 | ALA4431335 | single protein format | Scientific Literature | |
4. | ALA4432302 | B | Inhibition of recombinant human triosephosphate isomerase assessed as reduction of DHAP at 200 uM after 2 hrs by measuring NADH consumption by alpha-glycerolphosphate dehydrogenase coupled assay | Homo sapiens | 3 | ALA4431335 | single protein format | Scientific Literature | |
5. | ALA4432303 | F | Antitrypanosomal activity against epimastigote forms of Trypanosoma cruzi NINOA isolated from chagas disease patient after 24 hrs by resazurin dye based spectrophotometric analysis | Trypanosoma cruzi | 6 | ALA4431335 | organism-based format | Scientific Literature | |
6. | ALA4432304 | F | Antitrypanosomal activity against epimastigote forms of Trypanosoma cruzi INC-5 isolated from chagas disease patient after 24 hrs by resazurin dye based spectrophotometric analysis | Trypanosoma cruzi | 6 | ALA4431335 | organism-based format | Scientific Literature | |
7. | ALA4432305 | A | Cytotoxicity against mouse J774 cells assessed as decrease in cell viability after 24 hrs by resazurin assay | Mus musculus | 6 | ALA4431335 | cell-based format | Scientific Literature |