# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4433702 | B | Antagonist activity at human P2X1R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx | Homo sapiens | 8 | ALA4433213 | cell-based format | Scientific Literature | |
2. | ALA4433703 | B | Antagonist activity at P2X3R in mouse TG sensory neurons assessed as inhibition of P2X3R agonist alpha,beta-meATP-induced current at -65 mV holding potential by whole cell voltage clamp method | Mus musculus | 8 | ALA4433213 | single protein format | Scientific Literature | |
3. | ALA4433706 | B | Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx | Homo sapiens | 8 | ALA4433213 | cell-based format | Scientific Literature | |
4. | ALA4433707 | B | Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx relative to control | Homo sapiens | 8 | ALA4433213 | cell-based format | Scientific Literature | |
5. | ALA4433708 | B | Antagonist activity at human P2X3R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx | Homo sapiens | 8 | ALA4433213 | cell-based format | Scientific Literature | |
6. | ALA4433710 | B | Antagonist activity at human P2X4R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx | Homo sapiens | 8 | ALA4433213 | cell-based format | Scientific Literature | |
7. | ALA4433712 | B | Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influx | Homo sapiens | 8 | ALA4433213 | cell-based format | Scientific Literature | |
8. | ALA4433713 | B | Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influx relative to control | Homo sapiens | 7 | ALA4433213 | cell-based format | Scientific Literature | |
9. | ALA4433714 | B | Agonist activity at P2X3R in mouse TG sensory neurons assessed as induction of channel current at 1 uM at -65 mV holding potential by whole cell voltage clamp method relative to alpha,beta-meATP | Mus musculus | 1 | ALA4433213 | single protein format | Scientific Literature | |
10. | ALA4433715 | B | Agonist activity at P2X3R in mouse TG sensory neurons assessed as induction of channel current at 10 uM at -65 mV holding potential by whole cell voltage clamp method relative to alpha,beta-meATP | Mus musculus | 3 | ALA4433213 | single protein format | Scientific Literature | |
11. | ALA4433716 | B | Antagonist activity at GABAA receptor in mouse TG sensory neurons assesed as inhibition of GABAA receptor agonist GABA-evoked currents at 1 uM pre-applied before GABA addition | Mus musculus | 2 | ALA4433213 | assay format | Scientific Literature | |
12. | ALA4433717 | B | Antagonist activity at 5-HT3 receptor in mouse TG sensory neurons assessed as inhibition of 5-HT3 receptor agonist 5-HT-evoked currents at 1 uM pre-applied before 5-HT addition | Mus musculus | 2 | ALA4433213 | single protein format | Scientific Literature | |
13. | ALA4433718 | B | Selectivity ratio of IC50 for human P2X1R transfected in human P2X3R 1321N1 cells to IC50 for human transfected in human 1321N1 cells | Homo sapiens | 2 | ALA4433213 | cell-based format | Scientific Literature | |
14. | ALA4433719 | B | Selectivity ratio of IC50 for human P2X4R transfected in human P2X3R 1321N1 cells to IC50 for human transfected in human 1321N1 cells | Homo sapiens | 2 | ALA4433213 | cell-based format | Scientific Literature |