The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4346333 B Inhibition of human N-terminal His6 tagged BRD4 BD1 (57 to 168) residues expressed in Escherichia coli BL21(DE3) cells after 1 hr by TR-FRET assay Homo sapiens 49 cell-based format Scientific Literature 2. ALA4346334 B Inhibition of human N-terminal His6 tagged BRD4 BD2 (352 to 457) residues expressed in Escherichia coli BL21(DE3) cells after 1 hr by TR-FRET assay Homo sapiens 49 cell-based format Scientific Literature 3. ALA4346335 B Selectivity index, ratio of Ki for human N-terminal His6 tagged BRD4 BD1 (57 to 168) residues expressed in Escherichia coli BL21(DE3) cells to Ki for inhibition of human N-terminal His6 tagged BRD4 BD2 (352 to 457) residues expressed in Escherichia coli BL21(DE3) cells Homo sapiens 49 cell-based format Scientific Literature 4. ALA4346336 F Antiproliferative activity against human SKM1 cells assessed as reduction in cell viability after 5 days by CellTiter-Glo assay Homo sapiens 49 cell-based format Scientific Literature 5. ALA4346337 F Antiproliferative activity against human H1299 cells assessed as reduction in cell viability after 5 days by CellTiter-Glo assay Homo sapiens 49 cell-based format Scientific Literature 6. ALA4346338 A Unbound hepatic clearance in human liver microsomes Homo sapiens 45 microsome format Scientific Literature 7. ALA4346339 A Unbound hepatic clearance in mouse liver microsomes Mus musculus 41 microsome format Scientific Literature 8. ALA4346340 A Unbound hepatic clearance in rat liver microsomes Rattus norvegicus 41 microsome format Scientific Literature 9. ALA4346341 A Permeability in dog MDCK cells by PAMPA Canis lupus familiaris 45 cell-based format Scientific Literature 10. ALA4346342 A Oral bioavailability in mouse at 1 mg/kg Mus musculus 2 organism-based format Scientific Literature 11. ALA4346343 A AUC in dog at 0.3 mg/kg, po Canis lupus familiaris 2 organism-based format Scientific Literature 12. ALA4346344 A AUC in mouse at 1 mg/kg, po Mus musculus 2 organism-based format Scientific Literature 13. ALA4346345 A AUC in rat at 1 mg/kg, po Rattus norvegicus 2 organism-based format Scientific Literature 14. ALA4346346 A Half life in rat at 1 mg/kg, po Rattus norvegicus 2 organism-based format Scientific Literature 15. ALA4346347 A Half life in dog at 0.3 mg/kg, po Canis lupus familiaris 2 organism-based format Scientific Literature 16. ALA4346348 A Half life in mouse at 1 mg/kg, po Mus musculus 2 organism-based format Scientific Literature 17. ALA4346349 A Clearance in dog plasma at 0.1 mg/kg, iv Canis lupus familiaris 2 organism-based format Scientific Literature 18. ALA4346350 A Clearance in mouse plasma at 1 mg/kg, iv Mus musculus 2 organism-based format Scientific Literature 19. ALA4346351 A Clearance in rat plasma at 1 mg/kg, iv Rattus norvegicus 2 organism-based format Scientific Literature 20. ALA4346352 A AUC in dog at 0.1 mg/kg, iv Canis lupus familiaris 2 organism-based format Scientific Literature