| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4369833 | B | Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assay | Homo sapiens | 10 | ALA4368902 | cell-based format | Scientific Literature | |
| 2. | ALA4369834 | F | Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by HTRF assay | Homo sapiens | 10 | ALA4368902 | cell-based format | Scientific Literature | |
| 3. | ALA4369835 | F | Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by HTRF assay relative to control | Homo sapiens | 10 | ALA4368902 | cell-based format | Scientific Literature | |
| 4. | ALA4369844 | B | Induction of conformational changes in wild-type GHSR (unknown origin) assessed as effect on receptor conformation after 30 mins by FRET analysis | Homo sapiens | 7 | ALA4368902 | single protein format | Scientific Literature | |
| 5. | ALA4369845 | B | Inverse agonist activity at GHSR in Wistar rat pancreatic islets assessed as inhibition of ghrelin-induced insulinostatic action after 1 hr in presence of glucose | Rattus norvegicus | 1 | ALA4368902 | single protein format | Scientific Literature | |
| 6. | ALA4369846 | A | Effect on food intake in C57BL/6J mouse at 0.6 nmol/g body weight, sc measured after 2 hrs post dose | Mus musculus | 3 | ALA4368902 | organism-based format | Scientific Literature | |
| 7. | ALA4369847 | F | Anorexigenic activity in C57BL/6J mouse assessed as reduction in ghrelin-induced food intake at 0.6 nmol/g body weight, sc measured after 2 hrs post dose | Mus musculus | 3 | ALA4368902 | organism-based format | Scientific Literature |
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