| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4399407 | Binding | Agonist activity at human CAR transfected in human HepG2 cells cotransfected with CYP2B6 incubated for 23 hrs by luciferase reported gene assay | Homo sapiens | 29 | ALA4396920 | cell-based format | Scientific Literature | |
| 2. | ALA4399408 | Binding | Agonist activity at human CAR transfected in human HepG2 cells cotransfected with CYP2B6 incubated for 23 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 29 | ALA4396920 | cell-based format | Scientific Literature | |
| 3. | ALA4399409 | Binding | Ratio of Emax to EC50 for agonist activity at human CAR transfected in human HepG2 cells cotransfected with CYP2B6 by luciferase reporter gene assay | Homo sapiens | 26 | ALA4396920 | cell-based format | Scientific Literature | |
| 4. | ALA4399410 | ADME | Cytotoxicity against human HepG2 cells harbouring CYP2B6-hCAR gene assessed as reduction in cell viability at >10 uM incubated for 24 hrs by cell titer-Glo cell viability assay | Homo sapiens | 25 | ALA4396920 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!