# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4396049 | A | Cytotoxicity against human HET-1A cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay | Homo sapiens | 1 | ALA4393712 | cell-based format | Scientific Literature | |
2. | ALA4396050 | A | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay | Homo sapiens | 1 | ALA4393712 | cell-based format | Scientific Literature | |
3. | ALA4396051 | F | Antitumour activity against human SK-N-SH cells assessed as cell growth inhibition measured after 72 hrs by SRB assay | Homo sapiens | 21 | ALA4393712 | cell-based format | Scientific Literature | |
4. | ALA4396052 | F | Antitumour activity against mouse B16 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay | Mus musculus | 21 | ALA4393712 | cell-based format | Scientific Literature | |
5. | ALA4396053 | F | Antitumour activity against human EC109 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay | Homo sapiens | 21 | ALA4393712 | cell-based format | Scientific Literature | |
6. | ALA4396054 | F | Antitumour activity against human MGC803 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay | Homo sapiens | 21 | ALA4393712 | cell-based format | Scientific Literature | |
7. | ALA4396055 | F | Antitumour activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay | Homo sapiens | 21 | ALA4393712 | cell-based format | Scientific Literature | |
8. | ALA4396056 | F | Antitumour activity against human SMMC7721 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay | Homo sapiens | 21 | ALA4393712 | cell-based format | Scientific Literature | |
9. | ALA4396057 | A | Cytotoxicity against human HEK293 cells measured after 48 to 72 hrs by MTT assay | Homo sapiens | 8 | ALA4393712 | cell-based format | Scientific Literature | |
10. | ALA4396068 | P | Solubility of the compound in water | 8 | ALA4393712 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4396069 | A | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay | Homo sapiens | 1 | ALA4393712 | cell-based format | Scientific Literature | |
12. | ALA4396070 | F | Antiangiogenic activity in chicken chorioallantoic membrane assessed as reduction in neovascularization at 50 ug/ml measured after 72 hrs by CAM assay | Gallus gallus | 7 | ALA4393712 | cell membrane format | Scientific Literature | |
13. | ALA4396071 | F | Antitumour activity against human MCF7 cells xenografted in nude mouse assessed as decrease in tumour volume at 22.5 to 45 mg/kg/day, ip administered for 21 days | Homo sapiens | 1 | ALA4393712 | organism-based format | Scientific Literature | |
14. | ALA4396072 | F | Antitumour activity against human MCF7 cells xenografted in nude mouse assessed as decrease in tumour weight at 22.5 to 45 mg/kg/day, ip administered for 21 days | Homo sapiens | 1 | ALA4393712 | organism-based format | Scientific Literature | |
15. | ALA4396073 | T | Toxicity in nude mouse xenografted with human MCF7 cells assessed as increase in body weight at 22.5 to 45 mg/kg/day, ip administered for 21 days | Mus musculus | 1 | ALA4393712 | organism-based format | Scientific Literature | |
16. | ALA4396074 | T | Toxicity in nude mouse xenografted with human MCF7 cells assessed as effect on heart morphological changes at 22.5 to 45 mg/kg/day, ip administered for 21 days by HE staining analysis | Mus musculus | 1 | ALA4393712 | organism-based format | Scientific Literature | |
17. | ALA4396075 | T | Toxicity in nude mouse xenografted with human MCF7 cells assessed as effect on spleen morphological changes at 22.5 to 45 mg/kg/day, ip administered for 21 days by HE staining analysis | Mus musculus | 1 | ALA4393712 | organism-based format | Scientific Literature | |
18. | ALA4396076 | T | Toxicity in nude mouse xenografted with human MCF7 cells assessed as effect on lung morphological changes at 22.5 to 45 mg/kg/day, ip administered for 21 days by HE staining analysis | Mus musculus | 1 | ALA4393712 | organism-based format | Scientific Literature | |
19. | ALA4396077 | T | Toxicity in nude mouse xenografted with human MCF7 cells assessed as effect on kidney morphological changes at 22.5 to 45 mg/kg/day, ip administered for 21 days by HE staining analysis | Mus musculus | 1 | ALA4393712 | organism-based format | Scientific Literature | |
20. | ALA4396078 | T | Toxicity in nude mouse xenografted with human MCF7 cells assessed as liver edema at 22.5 to 45 mg/kg/day, ip administered for 21 days by HE staining analysis | Mus musculus | 1 | ALA4393712 | organism-based format | Scientific Literature |