| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4338731 | F | Agonist activity at human neurotensin receptor 1 expressed in CHO cells assessed as increase in intracellular calcium by Fluo-4 dye based fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 2. | ALA4338732 | F | Agonist activity at human neurotensin receptor 1 in HT-29 cells assessed as intracellular calcium mobilization by Fura-2 dye based spectrofluorimetry analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA4338735 | P | Chemical stability of fluorescent labelled compound in PBS buffer assessed as compound decomposition at pH 7.4 and 22 degree C after > 24 hrs by RP-HPLC analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA4338736 | B | Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation counter analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA4338737 | B | Displacement of [3H] UR-MK300 from human neurotensin receptor 1 stably expressed in CHO cells incubated in dark after 30 mins by liquid scintillation counter analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 6. | ALA4338738 | B | Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells preincubated for 20 mins to 2 hrs followed by addition of NT (8 to 13) measured upto 180 mins by FACSCalibur flow cytometry analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA4338739 | B | Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 60 mins in presence of NT (8 to 13) without compound washout by Hoechst H33342 staining confocal microscopy analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA4338740 | B | Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 75 mins in presence of NT (8 to 13) followed by compound washout with HBSS-BSA by Hoechst H33342 staining based confocal microscopy analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 9. | ALA4338741 | B | Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation counter analysis | Homo sapiens | 9 | cell-based format | Scientific Literature |
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