# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4320485 | F | Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by MTT assay | Homo sapiens | 71 | ALA4316595 | cell-based format | Scientific Literature | |
2. | ALA4320487 | F | Potency index, ratio of parthenolide IC50 to test compound IC50 for human MDA-MB-231 cells | Homo sapiens | 4 | ALA4316595 | cell-based format | Scientific Literature | |
3. | ALA4320488 | F | Antiproliferative activity against human SUM159 cells measured after 72 hrs by MTT assay | Homo sapiens | 9 | ALA4316595 | cell-based format | Scientific Literature | |
4. | ALA4320489 | F | Antiproliferative activity against human MCF7 cells measured after 72 hrs by MTT assay | Homo sapiens | 9 | ALA4316595 | cell-based format | Scientific Literature | |
5. | ALA4320490 | F | Antiproliferative activity against human Bcap37 cells measured after 72 hrs by MTT assay | Homo sapiens | 9 | ALA4316595 | cell-based format | Scientific Literature | |
6. | ALA4320491 | F | Antiproliferative activity against mouse 4T1 cells measured after 72 hrs by MTT assay | Mus musculus | 10 | ALA4316595 | cell-based format | Scientific Literature | |
7. | ALA4320492 | F | Potency index, ratio of parthenolide IC50 to test compound IC50 for human SUM159 cells | Homo sapiens | 8 | ALA4316595 | cell-based format | Scientific Literature | |
8. | ALA4320493 | F | Potency index, ratio of parthenolide IC50 to test compound IC50 for human MCF7 cells | Homo sapiens | 8 | ALA4316595 | cell-based format | Scientific Literature | |
9. | ALA4320494 | F | Potency index, ratio of parthenolide IC50 to test compound IC50 for human Bcap37 cells | Homo sapiens | 8 | ALA4316595 | cell-based format | Scientific Literature | |
10. | ALA4320495 | F | Potency index, ratio of parthenolide IC50 to test compound IC50 for mouse 4T1 cells | Mus musculus | 8 | ALA4316595 | cell-based format | Scientific Literature | |
11. | ALA4320496 | A | Cytotoxicity against mouse 3T3 cells measured after 72 hrs by MTT assay | Mus musculus | 2 | ALA4316595 | cell-based format | Scientific Literature | |
12. | ALA4320497 | T | Therapeutic index, ratio of IC50 for mouse 3T3 cells to IC50 for mouse 4T1 cells | Mus musculus | 2 | ALA4316595 | assay format | Scientific Literature | |
13. | ALA4320498 | F | Cell cycle arrest in human SUM159 cells assessed as decrease in S-phase accumulation at 0.5 hrs measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4316595 | cell-based format | Scientific Literature | |
14. | ALA4320499 | F | Cell cycle arrest in human SUM159 cells assessed as decrease in G2/M-phase accumulation at 0.5 hrs measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4316595 | cell-based format | Scientific Literature | |
15. | ALA4320500 | F | Cell cycle arrest in human SUM159 cells assessed as increase in G1-phase accumulation at 0.5 hrs measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4316595 | cell-based format | Scientific Literature | |
16. | ALA4320501 | F | Cell cycle arrest in human SUM159 cells assessed as down regulation of CHK2 expression at 0.1 to 0.2 uM measured after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4316595 | cell-based format | Scientific Literature | |
17. | ALA4320502 | B | Inhibition of Chk2 phosphorylation in human SUM159 cells at 0.1 to 0.2 uM measured after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4316595 | cell-based format | Scientific Literature | |
18. | ALA4320503 | F | Cell cycle arrest in human SUM159 cells assessed as down regulation of CHK1 expression at 0.1 to 0.2 uM measured after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4316595 | cell-based format | Scientific Literature | |
19. | ALA4320504 | B | Inhibition of Chk1 phosphorylation in human SUM159 cells at 0.1 to 0.2 uM measured after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4316595 | cell-based format | Scientific Literature | |
20. | ALA4320505 | B | Inhibition of CDC2 phosphorylation in human SUM159 cells at 0.1 to 0.2 uM measured after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4316595 | cell-based format | Scientific Literature |