# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4388634 | B | Inhibition of Mycobacterium tuberculosis His-tagged PtpB expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 30 mins by spectrophotometric method | Mycobacterium tuberculosis | 146 | assay format | Scientific Literature | ||
2. | ALA4388635 | B | Inhibition of human PTPN1 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric method | Homo sapiens | 146 | assay format | Scientific Literature | ||
3. | ALA4388636 | B | Inhibition of human PTPN2 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric method | Homo sapiens | 146 | assay format | Scientific Literature | ||
4. | ALA4388637 | B | Inhibition of human PTPN5 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric method | Homo sapiens | 146 | assay format | Scientific Literature | ||
5. | ALA4388638 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv after 5 days at 200 uM relative to control | Mycobacterium tuberculosis | 146 | organism-based format | Scientific Literature | ||
6. | ALA4388639 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv after 5 days | Mycobacterium tuberculosis | 51 | organism-based format | Scientific Literature | ||
7. | ALA4388640 | B | Inhibition of refolded rhodanese (unknown origin) preincubated with Escherichia coli GroEL/GroES for 60 mins by measuring rhodanese enzyme activity followed by compound addition by Fe(SCN)3 dye based spectrometric analysis | Homo sapiens | 58 | assay format | Scientific Literature | ||
8. | ALA4388641 | B | Inhibition of refolded pig heart mitochondrial MDH preincubated with Escherichia coli GroEL/GroES for 45 mins using sodium mesoxalate as substrate followed by compound addition and measured after 20 to 30 mins by spectrometric analysis | Sus scrofa | 58 | single protein format | Scientific Literature | ||
9. | ALA4388642 | B | Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured rhodanese refolding by measuring rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric analysis | Escherichia coli | 58 | assay format | Scientific Literature | ||
10. | ALA4388643 | B | Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured pig heart mitochondrial MDH refolding by measuring MDH enzyme activity using sodium mesoxalate as substrate after 20 to 40 mins by spectrometric analysis | Escherichia coli | 72 | assay format | Scientific Literature | ||
11. | ALA4388644 | B | Inhibition of human HSP60 expressed in Escherichia coli Rosetta 2(DE3)/human HSP10 expressed in Escherichia coli Rosetta 2(DE3) pLysS cells assessed as reduction in HSP60/HSP10-mediated denatured pig heart mitochondrial MDH refolding by measuring MDH enzyme activity using sodium mesoxalate as substrate after 40 to 60 mins by spectrometric analysis | Homo sapiens | 72 | cell-based format | Scientific Literature | ||
12. | ALA4388645 | A | Cytotoxicity against human THLE3 cells assessed as reduction in cell viability after 48 hrs by Alamar blue assay | Homo sapiens | 58 | cell-based format | Scientific Literature | ||
13. | ALA4388646 | A | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar blue assay | Homo sapiens | 58 | cell-based format | Scientific Literature |