# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4418739 | B | Inhibition of FTO (unknown origin) assessed as reduction in demethylation by measuring N6-mA and A level incubated for 2 hrs by HPLC-MS/MS analysis | Homo sapiens | 119 | ALA4418489 | single protein format | Patent Bioactivity Data | |
2. | ALA4418741 | B | Inhibition of COMT (unknown origin) at 200 nM in presence of AdoMet and Esculetin by reaction kinetic model based assay relative to control | Homo sapiens | 11 | ALA4418489 | single protein format | Patent Bioactivity Data | |
3. | ALA4418742 | B | Inhibition of COMT (unknown origin) at 50 nM in presence of AdoMet and Esculetin by reaction kinetic model based assay relative to control | Homo sapiens | 11 | ALA4418489 | single protein format | Patent Bioactivity Data | |
4. | ALA4418744 | A | Half life in rat liver microsomes at 2 uM in presence of NADPH incubated up to 60 mins by LC-MS/MS analysis | Rattus norvegicus | 20 | ALA4418489 | microsome format | Patent Bioactivity Data | |
5. | ALA4418745 | A | Clearance in rat liver microsomes assessed per mg protein at 2 uM in presence of NADPH incubated up to 60 mins by LC-MS/MS analysis | Rattus norvegicus | 20 | ALA4418489 | microsome format | Patent Bioactivity Data |