# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4325161 | Functional | Antiproliferative activity against human PANC1 cells incubated for 72 hrs by MTT assay | Homo sapiens | 7 | ALA4321870 | cell-based format | Scientific Literature | |
2. | ALA4325162 | Functional | Inhibition of colony formation in human PANC1 cells incubated for 14 days by crystal violet staining based assay | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
3. | ALA4325163 | Functional | Induction of apoptosis in human PANC1 cells assessed as increase in cleaved caspase-3 level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
4. | ALA4325164 | Functional | Induction of apoptosis in human PANC1 cells assessed as increase in cleaved PARP level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
5. | ALA4325165 | Binding | Inhibition of MEK1/2 in human PANC1 cells assessed as decrease in phosphorylated levels of MEK at S217/221 at 5 uM incubated for 24 hrs by Western blotting analysis | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
6. | ALA4325167 | Binding | Inhibition of MEK1/2 in human PANC1 cells assessed as decrease in phosphorylated levels of ERK(T202/Y204) at 5 uM incubated for 24 hrs by Western blotting analysis | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
7. | ALA4325168 | Binding | Inhibition of MEK1/2 in human PANC1 cells assessed as decrease in phosphorylated levels of ERK(T202/Y204) in nuclear fraction at 5 uM incubated for 24 hrs by Western blotting analysis | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
8. | ALA4325169 | Functional | Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay | Homo sapiens | 3 | ALA4321870 | cell-based format | Scientific Literature | |
9. | ALA4325170 | Functional | Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay | Homo sapiens | 3 | ALA4321870 | cell-based format | Scientific Literature | |
10. | ALA4325171 | Functional | Antiproliferative activity against human MCF cells incubated for 72 hrs by MTT assay | Homo sapiens | 3 | ALA4321870 | cell-based format | Scientific Literature | |
11. | ALA4325172 | Functional | Antiproliferative activity against human DU145 cells incubated for 72 hrs by MTT assay | Homo sapiens | 3 | ALA4321870 | cell-based format | Scientific Literature | |
12. | ALA4325173 | Functional | Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay | Homo sapiens | 3 | ALA4321870 | cell-based format | Scientific Literature |