#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4388501	Functional	Growth inhibition of human NCI-H2228 cells	Homo sapiens	6	ALA4387718	cell-based format	Scientific Literature
2.	ALA4388502	Functional	Growth inhibition of human NCI-H3122 cells	Homo sapiens	6	ALA4387718	cell-based format	Scientific Literature
3.	ALA4388503	Binding	Inhibition of wild-type ALK (unknown origin)	Homo sapiens	4	ALA4387718	single protein format	Scientific Literature
4.	ALA4388504	Binding	Inhibition of ALK L1196M mutant (unknown origin)	Homo sapiens	4	ALA4387718	single protein format	Scientific Literature
5.	ALA4388505	Binding	Inhibition of ALK F1174L mutant (unknown origin)	Homo sapiens	4	ALA4387718	single protein format	Scientific Literature
6.	ALA4388506	Functional	Antitumor activity against human NCI-H2228 cells harboring EML4-fused ALK variant xenografted in po dosed SCID Beige nude mouse assessed as tumor growth inhibition administered once daily for 14 days measured twice a week for 21 days during compound dosing	Homo sapiens	1	ALA4387718	organism-based format	Scientific Literature
7.	ALA4388507	Toxicity	Toxicity in SCID Beige nude mouse xenografted with human NCI-H2228 cells harboring EML4-fused ALK variant assessed as change in body weight at 30 mg/kg, po administered once daily for 14 days and measured twice per week for 14 days during compound dosing	Mus musculus	1	ALA4387718	organism-based format	Scientific Literature
8.	ALA4388508	Functional	Antitumor activity against human NCI-H2228 cells harboring EML4-fused ALK variant xenografted in SCID Beige nude mouse assessed as tumor growth inhibition at 10 mg/kg, po administered once daily for 14 days measured twice per week for 21 days during compound dosing relative to control	Homo sapiens	2	ALA4387718	organism-based format	Scientific Literature
9.	ALA4388509	Functional	Antitumor activity against human NCI-H2228 cells harboring EML4-fused ALK variant xenografted in SCID Beige nude mouse assessed as tumor growth inhibition at 30 mg/kg, po administered once daily for 14 days measured twice per week for 21 days during compound dosing relative to control	Homo sapiens	1	ALA4387718	organism-based format	Scientific Literature
10.	ALA4388510	ADME	Oral bioavailability in SCID Beige nude mouse xenografted with human NCI-H2228 cells harboring EML4-fused ALK variant at 3 to 30 mg/kg administered once daily for 14 days relative to control	Mus musculus	1	ALA4387718	organism-based format	Scientific Literature
11.	ALA4388511	ADME	Tmax in SCID Beige nude mouse xenografted with human NCI-H2228 cells harboring EML4-fused ALK variant at 3 to 30 mg/kg, po administered once daily for 14 days	Mus musculus	1	ALA4387718	organism-based format	Scientific Literature
12.	ALA4388512	ADME	Cmax in SCID Beige nude mouse xenografted with human NCI-H2228 cells harboring EML4-fused ALK variant at 3 to 30 mg/kg, po administered once daily for 14 days	Mus musculus	1	ALA4387718	organism-based format	Scientific Literature
13.	ALA4388513	ADME	AUC (0 to t) in SCID Beige nude mouse xenografted with human NCI-H2228 cells harboring EML4-fused ALK variant at 3 to 30 mg/kg, po administered once daily for 14 days	Mus musculus	1	ALA4387718	organism-based format	Scientific Literature