#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4417036	A	Drug recovery in iv dosed mouse feces	Mus musculus	9		organism-based format	Scientific Literature
2.	ALA4417037	A	Plasma clearance in cynomolgus monkey	Macaca fascicularis	1		assay format	Scientific Literature
3.	ALA4417038	B	Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and MnCl2 as co-facor preincubated for 15 mins followed by substrate addition and measured after 45 mins by AAO/horse radish peroxidase enzyme coupled assay	Homo sapiens	26		single protein format	Scientific Literature
4.	ALA4417039	B	Inhibition of MetAP2 in HUVEC assessed as reduction in viability incubated for 3 days by CyQUANT Direct Cell proliferation assay	Homo sapiens	26		cell-based format	Scientific Literature
5.	ALA4417040	A	Inhibition of N-terminal MetAP1 (unknown origin)	Homo sapiens	26		single protein format	Scientific Literature
6.	ALA4417041	B	Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 binding to recombinant full length N-terminal GFP-fused MetAP2 (unknown origin) expressed in HEK293 cells by Cheng-Prusoff equation analysis	Homo sapiens	4		cell-based format	Scientific Literature
7.	ALA4417042	B	Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 binding to recombinant full length N-terminal GFP-fused MetAP2 (unknown origin) expressed in HEK293 cells by FCCS analysis	Homo sapiens	4		cell-based format	Scientific Literature
8.	ALA4417043	B	Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 binding to recombinant full length N-terminal GFP-fused MetAP2 (unknown origin) expressed in HEK293 cells assessed as residence time by FCCS analysis	Homo sapiens	4		cell-based format	Scientific Literature
9.	ALA4417044	B	Binding affinity to MetAP2 in human A549 cells harboring siRNA pool at >=30 nM preincubated 4 hrs prior to compound washout and cell lysis followed by 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 probe addition and measured by fluorescence correlation spectroscopic method relative to control	Homo sapiens	4		cell-based format	Scientific Literature
10.	ALA4417048	P	Solubility of compound in PBS buffer		10		small-molecule physicochemical format	Scientific Literature
11.	ALA4417049	A	Permeability of the compound from apical to basolateral side in human Caco2 cells	Homo sapiens	10		cell-based format	Scientific Literature
12.	ALA4417050	A	Efflux ratio of permeability in human Caco2 cells	Homo sapiens	10		cell-based format	Scientific Literature
13.	ALA4417051	A	Protein binding in mouse plasma assessed as unbound fraction	Mus musculus	10		cell-free format	Scientific Literature
14.	ALA4417052	A	Protein binding in human plasma assessed as unbound fraction	Homo sapiens	10		cell-free format	Scientific Literature
15.	ALA4417053	A	AUC in mouse at 1 mg/kg, iv	Mus musculus	9		organism-based format	Scientific Literature
16.	ALA4417054	A	Ratio of unbound drug level in mouse to fIC50 for inhibition of MetAP2 in HUVEC cells		9		cell-based format	Scientific Literature
17.	ALA4417055	A	Plasma clearance in iv dosed mouse	Mus musculus	9		organism-based format	Scientific Literature
18.	ALA4417056	A	Volume of distribution at steady state in iv dosed mouse	Mus musculus	9		organism-based format	Scientific Literature
19.	ALA4417057	A	Half life in iv dosed mouse	Mus musculus	9		organism-based format	Scientific Literature
20.	ALA4417058	A	Plasma clearance in rat	Rattus norvegicus	1		assay format	Scientific Literature