# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4361912 | A | Cytotoxicity against human MCF7/Dox cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
2. | ALA4361913 | A | Cytotoxicity against human MCF7/Dox cells assessed as cell survival at 12.5 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
3. | ALA4361914 | B | Reversal of P-gp-mediated multidrug resistance in human MCF7/Dox cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 12.5 uM after 48 hrs by MTT assay (Rvb = 51.19 +/- 0.95 microM) | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
4. | ALA4361915 | B | Inhibition of P-gp-mediated drug resistance in human MCF7/Dox cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring ratio of doxorubicin IC50 in absence of test compound to doxorubicin IC50 in presence of test compound at 12.5 uM after 48 hrs by MTT assay | Homo sapiens | 34 | cell-based format | Scientific Literature |