# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4414012 | F | Cytotoxicity against human primary CLL cells assessed as cell death after 48 hrs by annexin V/propidium iodide-staining based flow cytometry | Homo sapiens | 21 | ALA4411330 | cell-based format | Scientific Literature | |
2. | ALA4414013 | F | Cytotoxicity against human JJN-3 cells assessed as cell death after 48 hrs by annexin V/propidium iodide-staining based flow cytometry | Homo sapiens | 21 | ALA4411330 | cell-based format | Scientific Literature | |
3. | ALA4414014 | A | Cytotoxicity against human B cells assessed as cell death after 48 hrs by annexin V/propidium iodide-staining based flow cytometry | Homo sapiens | 7 | ALA4411330 | cell-based format | Scientific Literature | |
4. | ALA4414015 | A | Cytotoxicity against human T cells assessed as cell death after 48 hrs by annexin V/propidium iodide-staining based flow cytometry | Homo sapiens | 7 | ALA4411330 | cell-based format | Scientific Literature | |
5. | ALA4414016 | T | Therapeutic index, ratio of LC50 for human B cells to LC50 for human primary CLL cells | Homo sapiens | 7 | ALA4411330 | assay format | Scientific Literature | |
6. | ALA4414017 | T | Therapeutic index, ratio of LC50 for human T cells to LC50 for human primary CLL cells | Homo sapiens | 7 | ALA4411330 | assay format | Scientific Literature | |
7. | ALA4414018 | B | Inhibition of NF-kappaB in human JJN-3 cells assessed as reduction in p65 DNA binding activity up to 30 nM after 4 hrs by ELISA | Homo sapiens | 5 | ALA4411330 | cell-based format | Scientific Literature | |
8. | ALA4414019 | B | Inhibition of NF-kappaB in human JJN-3 cells assessed as reduction in p50 DNA binding activity up to 30 nM after 4 hrs by ELISA | Homo sapiens | 6 | ALA4411330 | cell-based format | Scientific Literature | |
9. | ALA4414021 | B | Inhibition of NF-kappaB in human JJN-3 cells assessed as reduction in RelB DNA binding activity up to 30 nM after 4 hrs by ELISA | Homo sapiens | 6 | ALA4411330 | cell-based format | Scientific Literature |