# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4379686 | Binding | Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ uptake at 10 uM by Fluo-4/AM dye based fluorescence microplate reader assay relative to control | Homo sapiens | 19 | ALA4376837 | cell-based format | Scientific Literature | |
2. | ALA4379687 | Binding | Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ uptake by Fluo-4/AM dye based fluorescence microplate reader assay | Homo sapiens | 19 | ALA4376837 | cell-based format | Scientific Literature | |
3. | ALA4379688 | Binding | Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation counting method | Homo sapiens | 19 | ALA4376837 | cell-based format | Scientific Literature | |
4. | ALA4379689 | Functional | Antioxidant activity assessed as Trolox equivalents incubated for 15 mins by fluorescein based ORAC-FL assay | 19 | ALA4376837 | assay format | Scientific Literature | ||
5. | ALA4379690 | ADME | Permeability at 100 uM by PAMPA method | 19 | ALA4376837 | assay format | Scientific Literature | ||
6. | ALA4379691 | Binding | Inhibition of human recombinant AChE using acetylthiocholine iodide substrate by Ellman's protocol based assay | Homo sapiens | 16 | ALA4376837 | single protein format | Scientific Literature |