| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4328666 | B | Inhibition of human GST-tagged catalytic ROCK1 expressed in baculovirus system using STK S2 peptide substrate and and 33P-ATP after 60 mins by HTRF assay | Homo sapiens | 44 | ALA4325872 | assay format | Scientific Literature | |
| 2. | ALA4328667 | B | Inhibition of GST-fused human recombinant ROCK2 (11 to 552 residues) expressed in Spodoptera frugiperda insect cells using STK S2 peptide substrate and 33P-ATP after 60 mins by HTRF assay | Homo sapiens | 45 | ALA4325872 | cell-based format | Scientific Literature | |
| 3. | ALA4328668 | B | Inhibition of PKA (unknown origin) | Homo sapiens | 43 | ALA4325872 | assay format | Scientific Literature | |
| 4. | ALA4328669 | B | Selectivity ratio of IC50 for PKA (unknown origin) to IC50 for GST-fused human recombinant ROCK2 expressed in Spodoptera frugiperda insect cells | Homo sapiens | 29 | ALA4325872 | cell-based format | Scientific Literature | |
| 5. | ALA4328670 | P | Solubility of compound by high throughput assay | 13 | ALA4325872 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA4328671 | A | Protein binding in plasma (unknown origin) assessed as unbound fraction | Not specified | 14 | ALA4325872 | cell-free format | Scientific Literature | |
| 7. | ALA4328672 | A | Permeability of compound by PAMPA | 16 | ALA4325872 | assay format | Scientific Literature | ||
| 8. | ALA4328676 | B | Inhibition of ROCK1/2 in human PANC1 cells assessed as reduction in MYPT1 phosphorylation after 1 hr by ELISA | Homo sapiens | 14 | ALA4325872 | cell-based format | Scientific Literature |
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