# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4406418 | B | Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 10 | ALA4402606 | cell-based format | Scientific Literature | |
2. | ALA4406419 | B | Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 10 | ALA4402606 | cell-based format | Scientific Literature | |
3. | ALA4406420 | B | Ratio of IC50 for inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mins to IC50 for inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 10 | ALA4402606 | cell-based format | Scientific Literature | |
4. | ALA4406422 | A | Inhibition of recombinant human CYP4F2 expressed in baculovirus infected insect cells at 30 uM using Luc-4F2/3 as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 6 | ALA4402606 | cell-based format | Scientific Literature | |
5. | ALA4406423 | A | Inhibition of recombinant human CYP4F3A expressed in baculovirus infected insect cells at 30 uM using Luc-4F2/3 as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 6 | ALA4402606 | cell-based format | Scientific Literature | |
6. | ALA4406424 | A | Inhibition of recombinant human CYP4F3B expressed in baculovirus infected insect cells at 30 uM using Luc-4F2/3 as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 6 | ALA4402606 | cell-based format | Scientific Literature | |
7. | ALA4406425 | A | Inhibition of recombinant human CYP4F12 expressed in baculovirus infected insect cells at 30 uM using Luc-BE as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 8 | ALA4402606 | cell-based format | Scientific Literature |