# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4428988 | B | Inhibition of human recombinant AKR1C3 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 10 mins followed by protein addition by fluorometric assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
2. | ALA4428989 | B | Inhibition of human recombinant AKR1C2 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 10 mins followed by protein addition by fluorometric assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
3. | ALA4428990 | B | Selectivity ratio of IC50 for human recombinant AKR1C2 to IC50 for human recombinant AKR1C3 | Homo sapiens | 14 | assay format | Scientific Literature | ||
4. | ALA4428991 | B | Inhibition of COX1 in ram seminal vesicles using arachidonic acid as substrate assessed as reduction in PGH2 conversion to PGG2 by measuring TMPD oxidation preincubated for 5 mins followed by substrate/TMPD addition measured for 5 mins by colorimetric assay | Ovis aries | 4 | single protein format | Scientific Literature | ||
5. | ALA4428995 | B | Inhibition of COX2 (unknown origin) using arachidonic acid as substrate assessed as reduction in PGH2 conversion to PGG2 by measuring TMPD oxidation preincubated for 5 mins followed by substrate/TMPD addition measured for 5 mins by colorimetric assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
6. | ALA4428996 | B | Selectivity ratio of IC50 for inhibition of COX1 in ram seminal vesicles to IC50 for human recombinant AKR1C3 | 4 | assay format | Scientific Literature | |||
7. | ALA4429001 | B | Inhibition of human recombinant AKR1C2-mediated reduction of [3H]5alpha-DHT | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA4429002 | B | Inhibition of human recombinant AKR1C2-mediated reduction of [3H]5alpha-DHT at 100 uM | Homo sapiens | 1 | single protein format | Scientific Literature |