#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4433043	B	Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by TR-FRET assay	Homo sapiens	38	ALA4431389	assay format	Scientific Literature
2.	ALA4433044	B	Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluorescence polarization assay	Homo sapiens	38	ALA4431389	assay format	Scientific Literature
3.	ALA4433045	B	Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM addition measured after 3.5 hrs by flow cytometric analysis	Homo sapiens	38	ALA4431389	cell-based format	Scientific Literature
4.	ALA4433046	B	Inhibition of human ERG expressed in CHOK1 cell membranes after 2 hrs by cy3b-dofetilide-based fluorescence polarization assay	Homo sapiens	38	ALA4431389	cell-based format	Scientific Literature
5.	ALA4433048	B	Inhibition of LRRK2 (unknown origin)	Homo sapiens	2	ALA4431389	single protein format	Scientific Literature
6.	ALA4433050	B	Inhibition of JAK1 (unknown origin)	Homo sapiens	2	ALA4431389	single protein format	Scientific Literature
7.	ALA4433053	B	Selectivity ratio of IC50 for N-terminal 6His-tagged full length human Aurora B expressed in baculovirus to IC50 for 6His-tagged full length human recombinant SYK expressed in baculovirus	Homo sapiens	2	ALA4431389	assay format	Scientific Literature
8.	ALA4433054	B	Selectivity ratio of IC50 for LRRK2 (unknown origin) to IC50 for 6His-tagged full length human recombinant SYK expressed in baculovirus	Homo sapiens	2	ALA4431389	assay format	Scientific Literature
9.	ALA4433056	B	Selectivity ratio of IC50 for JAK1 (unknown origin) to IC50 for 6His-tagged full length human recombinant SYK expressed in baculovirus	Homo sapiens	2	ALA4431389	assay format	Scientific Literature
10.	ALA4433057	A	Clearance in rat blood at 3 mg/kg, po or 1 mg/kg, iv	Rattus norvegicus	7	ALA4431389	organism-based format	Scientific Literature
11.	ALA4433059	A	Oral bioavailability in rat at 3 mg/kg	Rattus norvegicus	7	ALA4431389	organism-based format	Scientific Literature
12.	ALA4433060	A	Cmax in rat at 3 mg/kg, po	Rattus norvegicus	8	ALA4431389	organism-based format	Scientific Literature
13.	ALA4433061	A	AUC in rat at 3 mg/kg, po	Rattus norvegicus	8	ALA4431389	organism-based format	Scientific Literature
14.	ALA4433062	P	Dissociation constant, pKa of the compound		8	ALA4431389	small-molecule physicochemical format	Scientific Literature
15.	ALA4433063	F	In vivo inhibition of SYK-stimulated Fc-gamma receptor mediated immune complex activation in po dosed CD rat assessed as reduction in cutaneous reverse passive Arthus reaction preincubated for 1 hr followed by ovalbumin challenge with Evans blue dye measured after 4 hrs by spectrophotometric analysis	Rattus norvegicus	1	ALA4431389	organism-based format	Scientific Literature
16.	ALA4433064	F	In vivo inhibition of SYK-stimulated Fc-gamma receptor mediated immune complex activation in CD rat assessed as reduction in cutaneous reverse passive Arthus reaction at 10 mg/kg, po preincubated for 1 hr followed by ovalbumin challenge with Evans blue dye measured after 4 hrs by spectrophotometric analysis	Rattus norvegicus	1	ALA4431389	organism-based format	Scientific Literature
17.	ALA4433065	F	In vivo inhibition of SYK-stimulated Fc-gamma receptor mediated immune complex activation in CD rat assessed as reduction in cutaneous reverse passive Arthus reaction at 30 mg/kg, po preincubated for 1 hr followed by ovalbumin challenge with Evans blue dye measured after 4 hrs by spectrophotometric analysis	Rattus norvegicus	1	ALA4431389	organism-based format	Scientific Literature
18.	ALA4433066	B	Inhibition of Aurora B in calyculin stimulated human HT29 cells assessed as reduction in phosphorylation of histone H3 at ser10	Homo sapiens	1	ALA4431389	assay format	Scientific Literature
19.	ALA4433067	T	Genotoxicity in Salmonella typhimurium TA1537 at 5000 ug/plate in presence of metabolic activation by Ames test	Salmonella enterica subsp. enterica serovar Typhimurium	1	ALA4431389	assay format	Scientific Literature
20.	ALA4433068	A	Half life in rat at 3 mg/kg, po or 1 mg/kg, iv	Rattus norvegicus	1	ALA4431389	organism-based format	Scientific Literature