| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4359340 | B | Partial agonist activity at Gal4-fused PPARdelta LBD (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assay | Homo sapiens | 12 | ALA4354876 | cell-based format | Scientific Literature | |
| 2. | ALA4359341 | B | Partial agonist activity at Gal4-fused PPARalpha LBD (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assay | Homo sapiens | 18 | ALA4354876 | cell-based format | Scientific Literature | |
| 3. | ALA4359342 | B | Partial agonist activity at Gal4-fused PPARalpha LBD (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assay relative to GW7647 | Homo sapiens | 18 | ALA4354876 | cell-based format | Scientific Literature | |
| 4. | ALA4359343 | B | Partial agonist activity at Gal4-fused PPARgamma LBD (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assay | Homo sapiens | 18 | ALA4354876 | cell-based format | Scientific Literature | |
| 5. | ALA4359344 | B | Partial agonist activity at Gal4-fused PPARgamma LBD (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assay relative to pioglitazone | Homo sapiens | 18 | ALA4354876 | cell-based format | Scientific Literature | |
| 6. | ALA4359345 | B | Partial agonist activity at Gal4-fused PPARdelta LBD (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assay relative to L165041 | Homo sapiens | 9 | ALA4354876 | cell-based format | Scientific Literature | |
| 7. | ALA4359347 | B | Selectivity ratio of EC50 for partial agonist activity at Gal4-fused PPARalpha LBD (unknown origin) expressed in HEK293T cells to EC50 for partial agonist activity at Gal4-fused PPARgamma LBD (unknown origin) expressed in HEK293T cells | Homo sapiens | 1 | ALA4354876 | cell-based format | Scientific Literature | |
| 8. | ALA4359348 | B | Selectivity ratio of EC50 for partial agonist activity at Gal4-fused PPARdelta LBD (unknown origin) expressed in HEK293T cells to EC50 for partial agonist activity at Gal4-fused PPARgamma LBD (unknown origin) expressed in HEK293T cells | Homo sapiens | 1 | ALA4354876 | cell-based format | Scientific Literature | |
| 9. | ALA4359349 | B | Agonist activity at RAR (unknown origin) at 10 uM | Homo sapiens | 1 | ALA4354876 | protein format | Scientific Literature | |
| 10. | ALA4359350 | B | Agonist activity at LXR (unknown origin) at 10 uM | Homo sapiens | 1 | ALA4354876 | protein format | Scientific Literature | |
| 11. | ALA4359351 | B | Agonist activity at FXR (unknown origin) at 10 uM | Homo sapiens | 1 | ALA4354876 | single protein format | Scientific Literature | |
| 12. | ALA4359352 | B | Agonist activity at RXR (unknown origin) at 10 uM | Homo sapiens | 1 | ALA4354876 | protein format | Scientific Literature | |
| 13. | ALA4359353 | A | Stability in Sprague-Dawley rat liver microsomes assessed as parent compound remaining at 10 uM after 60 mins by HPLC analysis | Rattus norvegicus | 1 | ALA4354876 | microsome format | Scientific Literature | |
| 14. | ALA4359354 | B | Partial agonist activity at recombinant N-terminal GFP-fused PPARgamma LBD (unknown origin) assessed as increase in biotinylated-CBP peptide recruitment measured after 2 hrs by HTRF assay | Homo sapiens | 3 | ALA4354876 | single protein format | Scientific Literature | |
| 15. | ALA4359355 | B | Partial agonist activity at recombinant N-terminal GFP-fused PPARgamma LBD (unknown origin) assessed as increase in biotinylated-SRC1 peptide recruitment measured after 2 hrs by HTRF assay | Homo sapiens | 2 | ALA4354876 | single protein format | Scientific Literature | |
| 16. | ALA4359356 | B | Partial agonist activity at recombinant PPARgamma LBD/N-terminal GFP-fused RXRalpha mutant LBD (unknown origin) assessed as increase in biotinylated-CBP peptide recruitment measured after 2 hrs by HTRF assay | Homo sapiens | 2 | ALA4354876 | assay format | Scientific Literature | |
| 17. | ALA4359357 | B | Partial agonist activity at recombinant PPARgamma LBD/N-terminal GFP-fused RXRalpha mutant LBD (unknown origin) assessed as increase in biotinylated-SRC1 peptide recruitment measured after 2 hrs by HTRF assay | Homo sapiens | 2 | ALA4354876 | assay format | Scientific Literature | |
| 18. | ALA4359362 | B | Selective modulation of PPARgamma in human HepG2 cells assessed as induction of adiponectin mRNA expression at 1 uM measured after 12 hrs by qPCR analysis | Homo sapiens | 2 | ALA4354876 | cell-based format | Scientific Literature | |
| 19. | ALA4359363 | A | Selective modulation of PPARgamma in human HepG2 cells assessed as induction of ANGPTL4 mRNA expression at 1 uM measured after 12 hrs by qPCR analysis | Homo sapiens | 1 | ALA4354876 | cell-based format | Scientific Literature | |
| 20. | ALA4359364 | A | Induction of adipogenesis in NHDF assessed as reduction in fibroblast differentiation into matured adipocytes at 0.2 to 20 uM administered on day 3 of differentiation 1 and day 5 of differentiation 2 followed by media refreshment at 2 days interval up to 13 days and measured on day 14 by Oil red O staining based light microscopic analysis | Homo sapiens | 1 | ALA4354876 | cell-based format | Scientific Literature |
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