# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4430738 | Binding | Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by ELISA | Agaricus bisporus | 30 | ALA4428110 | single protein format | Scientific Literature | |
2. | ALA4430739 | ADME | Cytotoxicity against mouse B16F10 cells assessed as reduction in cell viability at 50 uM after 24 hrs by CCK-8 assay | Mus musculus | 18 | ALA4428110 | cell-based format | Scientific Literature | |
3. | ALA4430740 | Binding | Activation of tyrosinase in mouse B16F10 cells assessed as melanin production at 50 uM after 48 hrs by spectrophotometric analysis relative to control | Mus musculus | 8 | ALA4428110 | cell-based format | Scientific Literature | |
4. | ALA4430741 | Binding | Potency index, ratio of compound activity to 8-MOP activity for tyrosinase activation in mouse B16F10 cells assessed as melanin production | Mus musculus | 3 | ALA4428110 | cell-based format | Scientific Literature |