| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4349318 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 3 hrs followed by LPS addition measured after 24 hrs by Griess assay | Mus musculus | 22 | cell-based format | Scientific Literature | ||
| 2. | ALA4349319 | B | Inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) using glucose as substrate preincubated for 10 mins followed by substrate addition in presence of ATP by G6PDH/NADP coupled assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 3. | ALA4349320 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Vmax using 3.125 uM ATP as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 0.019 OD/min) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 4. | ALA4349321 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Vmax using 6.25 uM ATP as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 0.019 OD/min) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA4349322 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Vmax using 12.5 uM ATP as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 0.019 OD/min) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA4349323 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Km using 3.125 uM ATP as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 1.62 mM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA4349324 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Km using 6.25 uM ATP as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 1.62 mM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA4349325 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Km using 12.5 uM ATP as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 1.62 mM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA4349326 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Vmax using 3.125 uM glucose as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 0.012 OD/min) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA4349327 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Vmax using 6.25 uM glucose as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 0.012 OD/min) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA4349328 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Vmax using 12.5 uM glucose as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 0.012 OD/min) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4349329 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Km using 3.125 uM glucose as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 0.64 mM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4349330 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Km using 6.25 uM glucose as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 0.64 mM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA4349331 | B | Non competitive inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) assessed as Km using 12.5 uM glucose as substrate by Lineweaver-Burk double reciprocal plot analysis (Rvb = 0.64 mM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4349332 | A | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability up to 100 uM after 24 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4349333 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced IL-1beta production preincubated for 3 hrs followed by LPS addition measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4349334 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced IL-6 production preincubated for 3 hrs followed by LPS addition measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4349335 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced COX2 protein expression preincubated for 3 hrs followed by LPS addition measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4349336 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS protein expression preincubated for 3 hrs followed by LPS addition measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4349337 | F | Inhibition of LPS-induced NFkappaB protein expression in mouse RAW264.7 cells at 12.5 to 50 uM preincubated for 3 hrs followed by LPS addition and measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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