# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4350304 | A | Cytotoxicity against mouse peritoneal macrophages up to 50 uM incubated for 24 hrs by neutral red assay | Mus musculus | 2 | ALA4346753 | cell-based format | Scientific Literature | |
2. | ALA4350309 | B | Activation of C-terminal His tagged human recombinant full length AMPK alpha1/beta1/gamma1 expressed in baculovirus infected Sf9 cells using SAMS peptide as substrate at 100 uM incubated for 60 mins by ADP-Glo luminescence assay relative to control | Homo sapiens | 16 | ALA4346753 | cell-based format | Scientific Literature | |
3. | ALA4350310 | B | Antagonist activity at AT1 receptor in rat portal vein assessed as reduction in potassium-induced contraction at 10 uM incubated for 1 min relative to control | Rattus norvegicus | 16 | ALA4346753 | assay format | Scientific Literature | |
4. | ALA4350311 | F | Antiplatelet activity in rabbit platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation at 100 uM relative to control | Oryctolagus cuniculus | 16 | ALA4346753 | cell-based format | Scientific Literature | |
5. | ALA4350312 | B | Inhibition of Cu2+ ion-induced oxidation of ascorbic acid by spectrophotometric analysis | 17 | ALA4346753 | assay format | Scientific Literature | ||
6. | ALA4350313 | B | Activation of C-terminal His tagged human recombinant full length AMPK alpha1/beta1/gamma1 expressed in baculovirus infected Sf9 cells using SAMS peptide as substrate incubated for 60 mins by ADP-Glo luminescence assay | Homo sapiens | 5 | ALA4346753 | cell-based format | Scientific Literature | |
7. | ALA4350314 | F | Inhibition of AGE formation assessed as reduction in bovin serum albumin glycation at 1 mM incubated for 24 hrs in presence of glucose by spectrophotometric analysis relative to control | 17 | ALA4346753 | assay format | Scientific Literature | ||
8. | ALA4350316 | F | Anti-inflammatory activity in mouse peritoneal macrophages assessed as inhibition of LPS-induced NO production incubated for 22 hrs by Griess reagent based colorimetric assay | Mus musculus | 3 | ALA4346753 | cell-based format | Scientific Literature | |
9. | ALA4350317 | A | Cytotoxicity against mouse peritoneal macrophages up to 50 uM incubated for 24 hrs by MTT assay | Mus musculus | 2 | ALA4346753 | cell-based format | Scientific Literature | |
10. | ALA4350321 | P | Solubility of the compound in PBS at pH 7.4 | 4 | ALA4346753 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4350322 | B | Activation of C-terminal His tagged human recombinant full length AMPK alpha1/beta1/gamma1 expressed in baculovirus infected Sf9 cells assessed as enzyme activation using SAMS peptide as substrate at 100 uM incubated for 60 mins by ADP-Glo luminescence assay relative to control | Homo sapiens | 4 | ALA4346753 | cell-based format | Scientific Literature |