| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4417691 | F | Antagonist activity at full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 100 mM sucralose by Fluo-4 dye based FLIPR assay (Rvb = 0.352 +/- 0.030 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 2. | ALA4417692 | F | Antagonist activity at full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 50 mM sucralose by Fluo-4 dye based FLIPR assay (Rvb = 0.192 +/- 0.011 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 3. | ALA4417693 | F | Antagonist activity at full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 25 mM sucralose by Fluo-4 dye based FLIPR assay (Rvb = 0.110 +/- 0.019 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 4. | ALA4417694 | F | Antagonist activity at full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 12.5 mM sucralose by Fluo-4 dye based FLIPR assay (Rvb = 0.051 +/- 0.004 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 5. | ALA4417695 | F | Antagonist activity at full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 6.25 mM sucralose by Fluo-4 dye based FLIPR assay (Rvb = 0.027 +/- 0.029 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 6. | ALA4417696 | F | Antagonist activity at full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 3.125 mM sucralose by Fluo-4 dye based FLIPR assay (Rvb = 0.030 +/- 0.042 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 7. | ALA4417697 | F | Antagonist activity at full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 1.5625 mM sucralose by Fluo-4 dye based FLIPR assay (Rvb = 0.042 +/- 0.039 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 8. | ALA4417698 | F | Antagonist activity at full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 0.7813 mM sucralose by Fluo-4 dye based FLIPR assay (Rvb = 0.038 +/- 0.042 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 9. | ALA4417699 | F | Antagonist activity at full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 0.3906 mM sucralose by Fluo-4 dye based FLIPR assay (Rvb = 0.046 +/- 0.048 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 10. | ALA4417700 | F | Effect on calcium flux in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 100 mM sucralose by Fluo-4 dye based FLIPR assay (Rvb = -0.179 +/- 0.023 No_unit) | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
| 11. | ALA4417701 | F | Antagonist activity at full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 10 mM phenyl-beta-glucopyranoside by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 12. | ALA4417702 | F | Antagonist activity at full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 5 mM phenyl-beta-glucopyranoside by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 13. | ALA4417703 | F | Antagonist activity at full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 2.5 mM phenyl-beta-glucopyranoside by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 14. | ALA4417704 | F | Antagonist activity at full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 1.25 mM phenyl-beta-glucopyranoside by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 15. | ALA4417705 | F | Antagonist activity at full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 0.625 mM phenyl-beta-glucopyranoside by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 16. | ALA4417706 | F | Antagonist activity at full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 0.3125 mM phenyl-beta-glucopyranoside by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 17. | ALA4417707 | F | Antagonist activity at full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 0.1563 mM phenyl-beta-glucopyranoside by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 18. | ALA4417708 | F | Antagonist activity at full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 0.0781 mM phenyl-beta-glucopyranoside by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 19. | ALA4417709 | F | Antagonist activity at full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 uM in presence of 0.0391 mM phenyl-beta-glucopyranoside by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 20. | ALA4417720 | F | Antagonist activity at full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as inhibition of sucralose-induced calcium flux at 25 uM by Fluo-4 dye based FLIPR assay | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data |
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