# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4422401 | B | Inhibition of human CYP2A6 expressed in insect cell microsomes assessed as reduction in enzyme-mediated coumarin 7-hydroxylation | Homo sapiens | 111 | ALA4421730 | assay format | Patent Bioactivity Data | |
2. | ALA4422402 | B | Selectivity index, ratio of IC50 for inhibition of human CYP3A4 assessed as reduction in enzyme-mediated testosterone 6-hydroxylation to IC50 for inhibition of human CYP2A6 assessed as reduction in enzyme-mediated coumarin 7-hydroxylation | Homo sapiens | 106 | ALA4421730 | assay format | Patent Bioactivity Data | |
3. | ALA4422403 | A | Inhibition of CYP3A4 in human liver microsomes assessed as reduction in enzyme-mediated testosterone 6-hydroxylation in presence of NADPH-generating system, G6P and G6P dehydrogenase | Homo sapiens | 106 | ALA4421730 | microsome format | Patent Bioactivity Data | |
4. | ALA4422410 | A | Inhibition of human CYP2E1 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method | Homo sapiens | 43 | ALA4421730 | single protein format | Patent Bioactivity Data | |
5. | ALA4422411 | A | Inhibition of human CYP2B6 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method | Homo sapiens | 43 | ALA4421730 | single protein format | Patent Bioactivity Data | |
6. | ALA4422412 | A | Inhibition of human CYP2C9 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method | Homo sapiens | 43 | ALA4421730 | single protein format | Patent Bioactivity Data | |
7. | ALA4422413 | A | Inhibition of human CYP2C19 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method | Homo sapiens | 43 | ALA4421730 | single protein format | Patent Bioactivity Data | |
8. | ALA4422414 | A | Inhibition of human CYP2D6 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method | Homo sapiens | 43 | ALA4421730 | single protein format | Patent Bioactivity Data | |
9. | ALA4422415 | B | Selectivity index, ratio of IC50 for inhibition of human CYP2E1 to IC50 for inhibition of human CYP3A4 | Homo sapiens | 42 | ALA4421730 | assay format | Patent Bioactivity Data | |
10. | ALA4422416 | B | Selectivity index, ratio of IC50 for inhibition of human CYP2B6 to IC50 for inhibition of human CYP3A4 | Homo sapiens | 42 | ALA4421730 | assay format | Patent Bioactivity Data | |
11. | ALA4422417 | B | Selectivity index, ratio of IC50 for inhibition of human CYP2C9 to IC50 for inhibition of human CYP3A4 | Homo sapiens | 42 | ALA4421730 | assay format | Patent Bioactivity Data | |
12. | ALA4422418 | B | Selectivity index, ratio of IC50 for inhibition of human CYP21C9 to IC50 for inhibition of human CYP3A4 | Homo sapiens | 42 | ALA4421730 | assay format | Patent Bioactivity Data | |
13. | ALA4422419 | B | Selectivity index, ratio of IC50 for inhibition of human CYP2D6 to IC50 for inhibition of human CYP3A4 | Homo sapiens | 42 | ALA4421730 | assay format | Patent Bioactivity Data |