| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4383532 | B | Inhibition of Myc-Max (unknown origin) expressed in human LNCAP cells assessed as reduction in transcriptional activity at 25 uM after 1 day by luciferase reporter gene assay relative to control | Homo sapiens | 12 | ALA4382207 | cell-based format | Scientific Literature | |
| 2. | ALA4383533 | B | Inhibition of Myc-Max (unknown origin) expressed in human LNCAP cells assessed as reduction in transcriptional activity after 1 day by luciferase reporter gene assay | Homo sapiens | 3 | ALA4382207 | cell-based format | Scientific Literature | |
| 3. | ALA4383534 | F | Cytotoxicity against human LNCAP cells assessed as reduction in cell viability after 96 hrs by prestoblue assay | Homo sapiens | 4 | ALA4382207 | cell-based format | Scientific Literature | |
| 4. | ALA4383535 | F | Cytotoxicity against human LNCAP cells assessed as reduction in cell viability at 3 uM after 96 hrs by prestoblue assay relative to control | Homo sapiens | 1 | ALA4382207 | cell-based format | Scientific Literature | |
| 5. | ALA4383536 | A | Cytotoxicity against rat HO15.19 cells assessed as reduction in cell viability at 25 uM after 96 hrs by prestoblue assay relative to control | Rattus norvegicus | 1 | ALA4382207 | cell-based format | Scientific Literature | |
| 6. | ALA4383537 | A | Cytotoxicity against rat HO15.19 cells assessed as reduction in cell viability at 3 uM after 96 hrs by prestoblue assay | Rattus norvegicus | 1 | ALA4382207 | cell-based format | Scientific Literature | |
| 7. | ALA4383538 | F | Induction of apoptosis in human LNCAP cells assessed as increase in PARP cleavage at 6.25 to 25 uM after 48 hrs by Western blot analysis | Homo sapiens | 2 | ALA4382207 | cell-based format | Scientific Literature | |
| 8. | ALA4383539 | B | Inhibition of biotin-labeled EBOX oligonucleotide binding to GST-tagged Myc (368 to 454 residues)/His-tagged Max (23 to 102 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) incubated up to 600 secs by biolayer interferometry assay | Homo sapiens | 1 | ALA4382207 | assay format | Scientific Literature | |
| 9. | ALA4383540 | B | Inhibition of full length Myc-Max (unknown origin) expressed in human PC3 cells at 12.5 to 25 uM after 24 hrs by luciferase reporter gene based mammalian two-hybrid assay | Homo sapiens | 2 | ALA4382207 | cell-based format | Scientific Literature | |
| 10. | ALA4383541 | B | Inhibition of Myc-Max (unknown origin) expressed in human 22rv1 cells harboring UBE2C promoter assessed as reduction in ARV7 level at 25 uM after 1 day by luciferase reporter gene assay relative to control | Homo sapiens | 8 | ALA4382207 | cell-based format | Scientific Literature | |
| 11. | ALA4383542 | B | Inhibition of Myc-Max (unknown origin) expressed in human 22rv1 cells harboring UBE2C promoter assessed as reduction in ARV7 level after 1 day by luciferase reporter gene assay | Homo sapiens | 12 | ALA4382207 | cell-based format | Scientific Literature | |
| 12. | ALA4383543 | B | Inhibition of Myc-Max (unknown origin) expressed in human 22rv1 cells harboring UBE2C promoter assessed as reduction in ARV7 level at 12.5 to 25 uM after 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA4382207 | cell-based format | Scientific Literature | |
| 13. | ALA4383544 | B | Inhibition of biotin-labeled EBOX oligonucleotide binding to GST-tagged Myc (368 to 454 residues)/His-tagged Max (23 to 102 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) at 500 uM incubated up to 600 secs by biolayer interferometry assay | Homo sapiens | 3 | ALA4382207 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!