# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4383245 | F | Induction of DNA-interstanded-cross-link formation in [32P]-labeled 49-mer duplex DNA (unknown origin) at 1 mM in absence of H2O2 after 16 hrs by PAGE relative to control | Not specified | 11 | ALA4382201 | assay format | Scientific Literature | |
2. | ALA4383246 | F | Induction of DNA-interstanded-cross-link formation in [32P]-labeled 49-mer duplex DNA (unknown origin) at 1 mM in presence of H2O2 after 16 hrs by PAGE relative to control | Not specified | 7 | ALA4382201 | assay format | Scientific Literature | |
3. | ALA4383267 | P | Solubility of the compound in PBS buffer at 10 mM at pH 7.4 by UV-based analysis | 6 | ALA4382201 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4383268 | A | Permeability of the compound at pH 7.4 by PAMPA | 8 | ALA4382201 | assay format | Scientific Literature | ||
5. | ALA4383271 | A | Induction of apoptosis in human lymphocytes at 10 uM after 24 hrs by Annexin V-FITC/propidium iodide-staining based flow cytometry | Homo sapiens | 2 | ALA4382201 | cell-based format | Scientific Literature | |
6. | ALA4383272 | F | Induction of DNA cross-linking activity in human CLL-derived lymphocytes assessed as increase in gammaH2AX formation at 1 uM after 24 hrs by flow cytometry | Homo sapiens | 1 | ALA4382201 | cell-based format | Scientific Literature | |
7. | ALA4383287 | F | Growth inhibition of human MDA-MB-468 cells after 48 hrs by fluorescence polarisation assay | Homo sapiens | 8 | ALA4382201 | cell-based format | Scientific Literature |