# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4405659 | B | Inhibition of recombinant human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins by colorimetric assay | Homo sapiens | 84 | ALA4402588 | cell-based format | Scientific Literature | |
2. | ALA4405660 | B | Inhibition of recombinant human CD73 expressed in CHO cells in 2 % DMSO using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins by colorimetric assay | Homo sapiens | 10 | ALA4402588 | cell-based format | Scientific Literature | |
3. | ALA4405661 | A | Metabolic stability in human Hepatocyte assessed as intrinsic clearance at 0.5 uM measured per 10'6 cells by LC-MS/MS analysis | Homo sapiens | 10 | ALA4402588 | cell-based format | Scientific Literature | |
4. | ALA4405662 | A | Metabolic stability in human Hepatocyte assessed as half life at 0.5 uM by LC-MS/MS analysis | Homo sapiens | 10 | ALA4402588 | cell-based format | Scientific Literature | |
5. | ALA4405663 | A | Inhibition of human liver microsome CYP1A2 using phenacetin as substrate incubated for 5 to 20 mins by LC-MS/MS analysis | Homo sapiens | 10 | ALA4402588 | microsome format | Scientific Literature | |
6. | ALA4405664 | A | Inhibition of human liver microsome CYP2C9 using diclofenac as substrate incubated for 5 to 20 mins by LC-MS/MS analysis | Homo sapiens | 10 | ALA4402588 | microsome format | Scientific Literature | |
7. | ALA4405665 | A | Inhibition of human liver microsome CYP2C19 using S-mephenytoin as substrate incubated for 5 to 20 mins by LC-MS/MS analysis | Homo sapiens | 10 | ALA4402588 | microsome format | Scientific Literature | |
8. | ALA4405666 | A | Inhibition of human liver microsome CYP2D6 using dextromethorphan as substrate incubated for 5 to 20 mins by LC-MS/MS analysis | Homo sapiens | 10 | ALA4402588 | microsome format | Scientific Literature | |
9. | ALA4405667 | A | Inhibition of human liver microsome CYP3A4 using midazolam as substrate incubated for 5 to 20 mins by LC-MS/MS analysis | Homo sapiens | 10 | ALA4402588 | microsome format | Scientific Literature | |
10. | ALA4405668 | B | Inhibition of human NTPDase 2 expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by colorimetric assay | Homo sapiens | 1 | ALA4402588 | cell-based format | Scientific Literature | |
11. | ALA4405669 | B | Inhibition of human NTPDase 3 expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by colorimetric assay | Homo sapiens | 1 | ALA4402588 | cell-based format | Scientific Literature | |
12. | ALA4405670 | B | Inhibition of human NTPDase 8 expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by colorimetric assay | Homo sapiens | 1 | ALA4402588 | cell-based format | Scientific Literature | |
13. | ALA4405671 | B | Inhibition of human CD39 expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by colorimetric assay | Homo sapiens | 1 | ALA4402588 | cell-based format | Scientific Literature |