# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4354897 | Binding | Binding affinity to Streptococcus mutans GtfB | Streptococcus mutans | 3 | ALA4354780 | assay format | Scientific Literature | |
2. | ALA4354898 | Binding | Binding affinity to Streptococcus mutans GtfC | Streptococcus mutans | 3 | ALA4354780 | assay format | Scientific Literature | |
3. | ALA4354902 | Functional | Antibiofilm activity against Streptococcus mutans assessed as inhibition of biofilm formation at 12.5 ug/ml relative to control | Streptococcus mutans | 1 | ALA4354780 | organism-based format | Scientific Literature | |
4. | ALA4679595 | Functional | Antibiofilm activity against Streptococcus mutans UA159 infected in Fischer 344 rat assessed as proximal surface score at 100 uM topically administered measured after 43 days | Streptococcus mutans | 2 | ALA4673385 | organism-based format | Scientific Literature | |
5. | ALA4679596 | Functional | Antibiofilm activity against Streptococcus mutans UA159 infected in Fischer 344 rat assessed as sulcal score at 100 uM topically administered measured after 43 days | Streptococcus mutans | 2 | ALA4673385 | organism-based format | Scientific Literature | |
6. | ALA4679597 | Functional | Antibiofilm activity against Streptococcus mutans UA159 infected in Fischer 344 rat assessed as buccal score at 100 uM topically administered measured after 43 days | Streptococcus mutans | 2 | ALA4673385 | organism-based format | Scientific Literature | |
7. | ALA4679598 | Binding | Inhibition of GtfD in Streptococcus mutans UA159 assessed as reduction in glucans level by Coomassie blue dye based SDS-PAGE analysis | Streptococcus mutans | 7 | ALA4673385 | single protein format | Scientific Literature | |
8. | ALA4679599 | Binding | Inhibition of GtfB in Streptococcus mutans UA159 assessed as reduction in glucans level by Coomassie blue dye based SDS-PAGE analysis | Streptococcus mutans | 7 | ALA4673385 | single protein format | Scientific Literature | |
9. | ALA4679600 | Binding | Inhibition of Gtf in Streptococcus mutans UA159 assessed as reduction in glucans level by Coomassie blue dye based SDS-PAGE analysis | Streptococcus mutans | 1 | ALA4673385 | assay format | Scientific Literature | |
10. | ALA4679601 | Binding | Inhibition of GtfC in Streptococcus mutans UA159 assessed as reduction in glucans level by Coomassie blue dye based SDS-PAGE analysis | Streptococcus mutans | 7 | ALA4673385 | single protein format | Scientific Literature | |
11. | ALA4679602 | Functional | Antibiofilm activity against Streptococcus mutans UA159 infected in Fischer 344 rat assessed as reduction in colony forming units at 100 uM topically administered measured after 43 days | Streptococcus mutans | 2 | ALA4673385 | organism-based format | Scientific Literature | |
12. | ALA4679604 | Functional | Bactericidal activity against Streptococcus mutans UA159 assessed as reduction in bacterial growth at 100 uM after 24 hrs | Streptococcus mutans | 90 | ALA4673385 | organism-based format | Scientific Literature | |
13. | ALA4679605 | Functional | Bactericidal activity against Streptococcus gordonii DL1 assessed as reduction in bacterial growth at 100 uM after 24 hrs | Streptococcus gordonii | 2 | ALA4673385 | assay format | Scientific Literature | |
14. | ALA4679606 | Functional | Bactericidal activity against Streptococcus sanguinis SK36 assessed as reduction in bacterial growth at 100 uM after 24 hrs | Streptococcus sanguinis | 2 | ALA4673385 | assay format | Scientific Literature | |
15. | ALA4679607 | Physicochemical | Solubility of compound in water | 90 | ALA4673385 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA4679608 | Functional | Antibiofilm activity against Streptococcus mutans UA159 assessed as inhibition of biofilm formation by serial dilution method | Streptococcus mutans | 90 | ALA4673385 | organism-based format | Scientific Literature |