# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4374441 | ADME | Hemolytic activity in human Erythrocytes at 50 +/- 0.8 uM relative to control | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
2. | ALA4374442 | ADME | Hemolytic activity in human Erythrocytes at 10 +/- 0.8 uM relative to control | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
3. | ALA4374443 | Functional | Induction of mitochondrial membrane potential loss in human M-HeLa cells assessed as collapsed mitochondrial membrane potential at 25 uM after 24 hrs by Jc-10 dye based flow cytometric analysis (Rvb = 22.17%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
4. | ALA4374444 | Functional | Induction of mitochondrial membrane potential loss in human M-HeLa cells assessed as intact mitochondrial membrane potential at 25 uM after 24 hrs by Jc-10 dye based flow cytometric analysis (Rvb = 77.48%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
5. | ALA4374445 | Functional | Induction of mitochondrial membrane potential loss in human M-HeLa cells assessed as collapsed mitochondrial membrane potential at 10 uM after 24 hrs by Jc-10 dye based flow cytometric analysis (Rvb = 22.17%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
6. | ALA4374446 | Functional | Induction of mitochondrial membrane potential loss in human M-HeLa cells assessed as intact mitochondrial membrane potential at 10 uM after 24 hrs by Jc-10 dye based flow cytometric analysis (Rvb = 77.48%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
7. | ALA4374447 | Functional | Induction of apoptosis in human M-HeLa cells assessed as necrotic cells at 25 uM after 24 hrs by annexin V-FITC/PIstaining based flow cytometric analysis (Rvb = 4.55%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
8. | ALA4374448 | Functional | Induction of apoptosis in human M-HeLa cells assessed as late apoptotic cells at 25 uM after 24 hrs by annexin V-FITC/PIstaining based flow cytometric analysis (Rvb = 0.62%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
9. | ALA4374449 | Functional | Induction of apoptosis in human M-HeLa cells assessed as early apoptotic cells at 25 uM after 24 hrs by annexin V-FITC/PIstaining based flow cytometric analysis (Rvb = 1.5%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
10. | ALA4374450 | Functional | Induction of apoptosis in human M-HeLa cells assessed as viable cells at 25 uM after 24 hrs by annexin V-FITC/PIstaining based flow cytometric analysis (Rvb = 93.33%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
11. | ALA4374451 | Functional | Induction of apoptosis in human M-HeLa cells assessed as necrotic cells at 10 uM after 24 hrs by annexin V-FITC/PIstaining based flow cytometric analysis (Rvb = 4.55%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
12. | ALA4374452 | Functional | Induction of apoptosis in human M-HeLa cells assessed as late apoptotic cells at 10 uM after 24 hrs by annexin V-FITC/PIstaining based flow cytometric analysis (Rvb = 0.62%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
13. | ALA4374453 | Functional | Induction of apoptosis in human M-HeLa cells assessed as early apoptotic cells at 10 uM after 24 hrs by annexin V-FITC/PIstaining based flow cytometric analysis (Rvb = 1.5%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
14. | ALA4374454 | Functional | Induction of apoptosis in human M-HeLa cells assessed as viable cells at 10 uM after 24 hrs by annexin V-FITC/PIstaining based flow cytometric analysis (Rvb = 93.33%) | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
15. | ALA4374455 | ADME | Cytotoxicity against human Chang liver cells assessed as reduction in cell viability after 24 hrs by DAPI/propidium iodide staining based assay | Homo sapiens | 17 | ALA4373667 | cell-based format | Scientific Literature | |
16. | ALA4374456 | Functional | Antiproliferative activity against human M-HeLa cells assessed as reduction in cell viability after 24 hrs by DAPI/propidium iodide staining based assay | Homo sapiens | 17 | ALA4373667 | cell-based format | Scientific Literature | |
17. | ALA4374457 | ADME | Hemolytic activity in human Erythrocytes at 100 +/- 7.8 uM relative to control | Homo sapiens | 3 | ALA4373667 | cell-based format | Scientific Literature | |
18. | ALA4374458 | Functional | Antiproliferative activity against human MCF7cells assessed as reduction in cell viability after 24 hrs by DAPI/propidium iodide staining based assay | Homo sapiens | 17 | ALA4373667 | cell-based format | Scientific Literature |