| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4418462 | B | Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hrs by FRET assay | Homo sapiens | 228 | single protein format | Patent Bioactivity Data | ||
| 2. | ALA4418463 | B | Inhibition of recombinant His-tagged human ATG7 at 0.123 uM incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hrs by FRET assay relative to control | Homo sapiens | 76 | single protein format | Patent Bioactivity Data | ||
| 3. | ALA4730107 | A | Antiproliferative activity against human H1650 cells assessed as reduction in cell viability after 72 hrs by cell titer glow assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
| 4. | ALA4730108 | B | Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hrs by FRET assay relative to control | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 5. | ALA4730109 | B | Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 4 hrs by Western blot analysis | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 6. | ALA4730110 | F | Induction of autophagy in human H4 cells assessed as decrease in LC3B spot area by immunofluorescence assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
| 7. | ALA4730116 | B | Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysis | Homo sapiens | 30 | cell-based format | Scientific Literature |
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