# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4323785 | Functional | Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed by agonist solution addition after 60 mins by cell based TR-FRET assay | Homo sapiens | 35 | ALA4321836 | cell-based format | Scientific Literature | |
2. | ALA4323799 | Physicochemical | Lipophilicity, logD of the compound at pH 7.5 by reversed-phase HPLC | 32 | ALA4321836 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4323800 | ADME | Clearance in human liver microsomes at 1 uM measured after 2 to 60 mins in presence of glucose-6-phosphate by LC-MS/MS analysis | Homo sapiens | 30 | ALA4321836 | microsome format | Scientific Literature | |
4. | ALA4323801 | ADME | Maximum oral bioavailability in human liver microsomes based well stirred liver model at 1 uM measured after 2 to 60 mins in presence of glucose-6-phosphate by LC-MS/MS analysis | Homo sapiens | 30 | ALA4321836 | organism-based format | Scientific Literature |