Antidepressant-like activity in albino Swiss CD-1 mouse assessed as reduction in immobility at 10 mg/kg, ip pretreated for 30 mins and measured after 6 mins by force swim test relative to control
Displacement of [3H]ketanserin from 5-HT2 receptor in Wistar rat brain cortex membrane at 10 uM after 40 mins by scintillation counting analysis relative to control
Anxiolytic activity in albino Swiss CD-1 mouse assessed as increase in number of punished crossings at 5 mg/kg, ip administered 30 mins prior to test by four-plate test relative to control
Anxiolytic activity in albino Swiss CD-1 mouse assessed as increase in number of punished crossings at 20 mg/kg, ip administered 30 mins prior to test by four-plate test relative to control
Mutagenicity in Salmonella typhimurium TA100 at 0.5 ug/plate preincubated for 20 mins followed by addition of top agar and measured after 48 hrs by Ames test
Mutagenicity in Salmonella typhimurium TA100 at 5 ug/plate preincubated for 20 mins followed by addition of top agar and measured after 48 hrs by Ames test
Mutagenicity in Salmonella typhimurium TA100 at 50 ug/plate preincubated for 20 mins followed by addition of top agar and measured after 48 hrs by Ames test