# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4386403 | Binding | Inhibition of HDAC6 in human BE(2)-C cells assessed as increase in tubulin acetylation at 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4385610 | cell-based format | Scientific Literature | |
2. | ALA4386404 | Binding | Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assay | Homo sapiens | 29 | ALA4385610 | single protein format | Scientific Literature | |
3. | ALA4386405 | Binding | Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter gene-based BRET assay | Homo sapiens | 29 | ALA4385610 | cell-based format | Scientific Literature | |
4. | ALA4386406 | Binding | Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter gene-based BRET assay | Homo sapiens | 19 | ALA4385610 | cell-based format | Scientific Literature | |
5. | ALA4386407 | Binding | Selectivity ratio of compound effect for inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells to compound effect for inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells | Homo sapiens | 19 | ALA4385610 | cell-based format | Scientific Literature | |
6. | ALA4386413 | Binding | Inhibition of HDAC10 in human BE(2)-C cells assessed as expansion of lysosomal compartment at 0.1 to 10 uM incubated for 24 hrs by LysoTracker Red DND-99 probe-based fluorescence assay | Homo sapiens | 7 | ALA4385610 | cell-based format | Scientific Literature |