# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4368350 | B | Inhibition of CD95 (unknown origin)/PLCgamma-1 SH3 domain (unknown origin) protein-protein interaction transfected in HEK293T cells incubated for 1 hr by renilla luciferase based protein-fragment complementation assay | Homo sapiens | 11 | ALA4364338 | cell-based format | Scientific Literature | |
2. | ALA4368351 | B | Inhibition of CD95 (unknown origin)/FADD (unknown origin) protein-protein interaction transfected in HEK293T cells incubated for 1 hr by renilla luciferase based protein-fragment complementation assay | Homo sapiens | 11 | ALA4364338 | cell-based format | Scientific Literature | |
3. | ALA4368352 | B | Selectivity index, ratio of IC50 for CD95 (unknown origin)/FADD (unknown origin) protein-protein interaction transfected in HEK293T cells to IC50 for CD95 (unknown origin)/PLCgamma-1 SH3 domain (unknown origin) protein-protein interaction transfected in HEK293T cells | Homo sapiens | 10 | ALA4364338 | cell-based format | Scientific Literature | |
4. | ALA4434521 | B | Inhibition of human full length HA-tagged CD95/human full length Myc-tagged PLCgamma1 protein-protein interaction transfected in HEK293T cells incubated for 4 hrs by renilla luciferase based protein-fragment complementation assay | Homo sapiens | 7 | ALA4433261 | cell-based format | Scientific Literature | |
5. | ALA4434522 | B | Inhibition of human full length HA-tagged CD95/FADD (unknown origin) protein-protein interaction transfected in HEK293T cells incubated for 4 hrs by renilla luciferase based protein-fragment complementation assay | Homo sapiens | 7 | ALA4433261 | cell-based format | Scientific Literature | |
6. | ALA4434523 | B | Selectivity ratio of IC50 for human full length HA-tagged CD95/FADD (unknown origin) protein-protein interaction to IC50 for human full length HA-tagged CD95/human full length Myc-tagged PLCgamma1 protein-protein interaction | Homo sapiens | 7 | ALA4433261 | assay format | Scientific Literature | |
7. | ALA4434524 | A | Half life in human whole blood | Homo sapiens | 2 | ALA4433261 | tissue-based format | Scientific Literature | |
8. | ALA4434525 | B | Inhibition of s-CD95L(unknown origin)-stimulated cell migration of human MDA-MB-231 cells at 1 uM incubated for 24 hrs by Boyden chambers assay | Homo sapiens | 1 | ALA4433261 | cell-based format | Scientific Literature | |
9. | ALA4434527 | B | Inhibition of s-CD95L(unknown origin)-stimulated cell migration of human MDA-MB-231 cells at 1 uM incubated for 24 hrs by Giemsa-staining based assay | Homo sapiens | 1 | ALA4433261 | cell-based format | Scientific Literature | |
10. | ALA4434529 | B | Inhibition of s-CD95L(unknown origin)-stimulated cell migration of human Th17 cells at 1 uM incubated for 24 hrs by Boyden chambers assay | Homo sapiens | 1 | ALA4433261 | assay format | Scientific Literature |