# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4421023 | F | Agonist activity at human amylin receptor expressed in BHK570 cells co-expressing RAMP3 assessed as increase in intracellular cAMP concentration incubated for 3 hrs in absence of albumin by CRE luciferase reporter gene assay | Homo sapiens | 143 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4421024 | F | Agonist activity at human calcitonin receptor expressed in BHK570 cells assessed as increase in intracellular cAMP concentration incubated for 3 hrs in absence of albumin by CRE luciferase reporter gene assay | Homo sapiens | 143 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4421025 | F | Agonist activity at human amylin receptor expressed in BHK570 cells co-expressing RAMP3 assessed as increase in intracellular cAMP concentration incubated for 3 hrs in presence of 10% FBS by CRE luciferase reporter gene assay | Homo sapiens | 96 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4421026 | F | Agonist activity at human calcitonin receptor expressed in BHK570 cells assessed as increase in intracellular cAMP concentration incubated for 3 hrs in presence of 10% FBS by CRE luciferase reporter gene assay | Homo sapiens | 96 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4421029 | P | Solubility in 100 mM glycylglycine buffer at pH 3.0 incubated for 18 hrs by UPLC analysis | 130 | small-molecule physicochemical format | Patent Bioactivity Data | |||
6. | ALA4421030 | P | Solubility in 100 mM glycylglycine buffer at pH 4.0 incubated for 18 hrs by UPLC analysis | 130 | small-molecule physicochemical format | Patent Bioactivity Data | |||
7. | ALA4421031 | P | Solubility in 100 mM bistrispropane buffer at pH 6.0 incubated for 18 hrs by UPLC analysis | 130 | small-molecule physicochemical format | Patent Bioactivity Data | |||
8. | ALA4421032 | P | Solubility in 100 mM glycylglycine buffer at pH 5.0 incubated for 18 hrs by UPLC analysis | 130 | small-molecule physicochemical format | Patent Bioactivity Data | |||
9. | ALA4421033 | P | Solubility in 100 mM bistrispropane buffer at pH 6.5 incubated for 18 hrs by UPLC analysis | 130 | small-molecule physicochemical format | Patent Bioactivity Data | |||
10. | ALA4421034 | P | Solubility in 100 mM bistrispropane buffer at pH 7.0 incubated for 18 hrs by UPLC analysis | 130 | small-molecule physicochemical format | Patent Bioactivity Data | |||
11. | ALA4421035 | P | Solubility in 100 mM bistrispropane buffer at pH 7.5 incubated for 18 hrs by UPLC analysis | 130 | small-molecule physicochemical format | Patent Bioactivity Data | |||
12. | ALA4421036 | P | Solubility in 100 mM bistrispropane buffer at pH 8.0 incubated for 18 hrs by UPLC analysis | 130 | small-molecule physicochemical format | Patent Bioactivity Data | |||
13. | ALA4421072 | B | Displacement of [125I]-labeled rat amylin from human amylin receptor expressed in BHK tkts13 whole cells co-expressing RAMP3 incubated for 60 mins by scintillation proximity assay | Homo sapiens | 91 | cell-based format | Patent Bioactivity Data | ||
14. | ALA4421073 | B | Displacement of [125I]-labeled human calcitonin from human calcitonin receptor expressed in BHK tkts13 whole cells incubated for 60 mins by scintillation proximity assay | Homo sapiens | 91 | cell-based format | Patent Bioactivity Data |