# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4322409 | B | Inhibition of mouse NKX2-5 expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as protein-induced transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control | Mus musculus | 10 | cell-based format | Scientific Literature | ||
2. | ALA4322414 | B | Inhibition of mouse GATA4/mouse NKX2-5 protein-protein interaction expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as transcriptional synergy at 10 uM after 24 hrs by luciferase reporter gene assay relative to control | Mus musculus | 10 | cell-based format | Scientific Literature | ||
3. | ALA4322416 | B | Inhibition of mouse GATA4 expressed in Chlorocebus aethiops COS1 cells harboring NP-112 reporter gene assessed as BNP promoter-driven transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control | Mus musculus | 10 | cell-based format | Scientific Literature | ||
4. | ALA4322420 | A | Induction of necrosis in Chlorocebus aethiops COS1 cells assessed as LDH release at 1 to 30 uM after 24 hrs by LDH assay relative to control | Chlorocebus aethiops | 40 | cell-based format | Scientific Literature | ||
5. | ALA4322421 | A | Cytotoxicity against Chlorocebus aethiops COS1 cells assessed as reduction in cell viability at 10 uM after 24 hrs by MTT assay relative to control | Chlorocebus aethiops | 10 | cell-based format | Scientific Literature | ||
6. | ALA4322422 | A | Cytotoxicity against Chlorocebus aethiops COS1 cells assessed as reduction in cell viability at 10 uM after 24 hrs by CellTiter-Glo Luminescent Cell Viability assay relative to control | Chlorocebus aethiops | 6 | cell-based format | Scientific Literature |