#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4360333	Binding	Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by amplex red staining-based horseradish peroxidase/glutamate oxidase coupled assay	Homo sapiens	26	ALA4359817	assay format	Scientific Literature
2.	ALA4360334	Binding	Inhibition of GLS2 (unknown origin)	Homo sapiens	16	ALA4359817	single protein format	Scientific Literature
3.	ALA4360335	Binding	Inhibition of GLS in human PC3 cells using glutamine as substrate measured after 6 hrs by amplex red staining-based horseradish peroxidase/glutamate oxidase coupled assay	Homo sapiens	26	ALA4359817	cell-based format	Scientific Literature
4.	ALA4360336	Functional	Antiproliferative activity against human NCI-H1703 cells assessed as reduction in cell growth after 5 days by SYTOX green staining-based assay	Homo sapiens	10	ALA4359817	cell-based format	Scientific Literature
5.	ALA4360337	Physicochemical	Thermodynamic aqueous solubility of the compound at pH 7.4		21	ALA4359817	small-molecule physicochemical format	Scientific Literature
6.	ALA4360338	Physicochemical	Lipophilicity, log D of the compound at pH 7.4		22	ALA4359817	small-molecule physicochemical format	Scientific Literature
7.	ALA4360339	ADME	Intrinsic clearance in human hepatocytes assessed per million cells	Homo sapiens	4	ALA4359817	cell-based format	Scientific Literature
8.	ALA4360340	ADME	Intrinsic clearance in human microsomes	Homo sapiens	8	ALA4359817	microsome format	Scientific Literature
9.	ALA4360341	ADME	Protein binding in human plasma assessed as unbound fraction by LC-MS-based equilibrium dialysis analysis	Homo sapiens	8	ALA4359817	cell-free format	Scientific Literature
10.	ALA4360342	ADME	Intrinsic clearance in rat hepatocytes assessed per million cells	Rattus norvegicus	7	ALA4359817	cell-based format	Scientific Literature
11.	ALA4360343	ADME	Clearance in iv or po dosed Han Wistar rat	Rattus norvegicus	5	ALA4359817	organism-based format	Scientific Literature
12.	ALA4360344	ADME	Volume of distribution at steady state in iv or po dosed Han Wistar rat	Rattus norvegicus	5	ALA4359817	organism-based format	Scientific Literature
13.	ALA4360345	ADME	Oral bioavailability in Han Wistar rat	Rattus norvegicus	5	ALA4359817	organism-based format	Scientific Literature
14.	ALA4360387	ADME	Time at which plasma concentration stays above in vitro GI50 for antiproliferative activity against human NCI-H1703 cells in SCID mouse at 100 mg/kg, po	Mus musculus	1	ALA4359817	organism-based format	Scientific Literature
15.	ALA4360388	ADME	Clearance in CD1 mouse at 100 mg/kg, po	Mus musculus	1	ALA4359817	organism-based format	Scientific Literature