| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4413700 | T | Mitochondrial toxicity in human HepG2 cells assessed as reduction in cell viability after 14 days in presence of glucose supplemented media by ATP depletion assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4413701 | T | Mitochondrial toxicity in human HepG2 cells assessed as reduction in cell viability after 3 days in presence of galactose supplemented media by ATP depletion assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4413702 | T | Mitochondrial toxicity in human HepG2 cells assessed as reduction in cell viability after 3 days in presence of glucose supplemented media by ATP depletion assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4413703 | T | Mitochondrial toxicity in human HepG2 cells assessed as lactic acid production at 50 uM followed by medium plus drugs replenishment every 3 to 4 days for 14 days relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA4413704 | B | Inhibition of NS5B polymerase in HCV genotype 1b/3a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysis | Hepatitis C virus | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4413705 | B | Inhibition of NS5B polymerase in HCV genotype 1b/4a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysis | Hepatitis C virus | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4413706 | B | Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 5 days by RT-PCR analysis | Hepatitis C virus subtype 2a | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4413707 | B | Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 5 days by RT-PCR analysis | Hepatitis C virus subtype 1a | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4413709 | B | Inhibition of NS5B polymerase in wild type HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assay | Hepatitis C virus subtype 1b | 11 | cell-based format | Scientific Literature | ||
| 10. | ALA4413710 | A | Cytotoxicity against human HuH7 cells assessed reduction in cell viability after 3 to 5 days by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 11. | ALA4413711 | A | Cytotoxicity against human PBMC assessed reduction in cell viability after 5 days by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 12. | ALA4413712 | A | Cytotoxicity against human CCRF-CEM assessed reduction in cell viability after 4 days by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 13. | ALA4413713 | A | Cytotoxicity against African green monkey Vero cells assessed reduction in cell viability after 3 days by MTT assay | Chlorocebus sabaeus | 11 | cell-based format | Scientific Literature | ||
| 14. | ALA4413714 | B | Inhibition of NS5B polymerase in HCV genotype 1b/5a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysis | Hepatitis C virus | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4413715 | B | Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assay | Hepatitis C virus subtype 1b | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4413716 | B | Selectivity ratio of EC50 for HCV genotype 1a NS5B polymerase to EC50 for wild type HCV genotype 1b NS5B polymerase | Hepatitis C virus | 3 | assay format | Scientific Literature | ||
| 17. | ALA4413717 | B | Selectivity ratio of EC50 for HCV genotype 2a NS5B polymerase to EC50 for wild type HCV genotype 1b NS5B polymerase | Hepatitis C virus | 3 | assay format | Scientific Literature | ||
| 18. | ALA4413718 | B | Selectivity ratio of EC50 for HCV genotype 1b/3a chimeric replicon NS5B polymerase to EC50 for wild type HCV genotype 1b NS5B polymerase | Hepatitis C virus | 3 | assay format | Scientific Literature | ||
| 19. | ALA4413719 | B | Selectivity ratio of EC50 for HCV genotype 1b/4a chimeric replicon NS5B polymerase to EC50 for wild type HCV genotype 1b NS5B polymerase | Hepatitis C virus | 3 | assay format | Scientific Literature | ||
| 20. | ALA4413720 | B | Selectivity ratio of EC50 for HCV genotype 1b/5a chimeric replicon NS5B polymerase to EC50 for wild type HCV genotype 1b NS5B polymerase | Hepatitis C virus | 3 | assay format | Scientific Literature |
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