#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4380042	B	Inverse agonist activity at human N-terminal His6-tagged RORgammat LBD (265 to 518 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition of N-terminal biotinylated co-activator SRC1 box2 peptide recruitment measured after 30 mins by TR-FRET assay	Homo sapiens	19	ALA4376852	assay format	Scientific Literature
2.	ALA4380047	A	Inverse agonist activity at His6-tagged PPARgamma LBD (unknown origin) assessed as inhibition of rosiglitazone-induced N-terminal biotinylated co-activator SRC1 box2 peptide recruitment measured after 30 mins by TR-FRET assay	Homo sapiens	19	ALA4376852	single protein format	Scientific Literature
3.	ALA4380049	B	Inverse agonist activity at RORgammat in mouse EL4 cells assessed as inhibition of PMA/ionomycin-induced IL-17a production at 10 uM preincubated for 24 hrs followed by PMA/ionomycin stimulation and measured after 5 hrs by SYBR green dye based qRT-PCR analysis relative to control	Mus musculus	3	ALA4376852	cell-based format	Scientific Literature
4.	ALA4380050	P	Chemical stability of the compound in pH 7.4 aqueous buffer assessed as parent compound remaining at 2 uM measured after 24 hrs by LC-MS analysis		4	ALA4376852	small-molecule physicochemical format	Scientific Literature
5.	ALA4380051	P	Kinetic solubility of the compound in pH 7.4 aqueous buffer at 500 uM measured after 90 mins by spectrophotometric method		4	ALA4376852	small-molecule physicochemical format	Scientific Literature
6.	ALA4380052	A	Permeability of the compound at 500 uM after 20 hrs by PAMPA		4	ALA4376852	assay format	Scientific Literature
7.	ALA4380053	A	Intrinsic clearance in human liver microsomes at 3 uM measured up to 90 mins in presence of metabolic phase 1 cofactors by LC-MS analysis	Homo sapiens	4	ALA4376852	microsome format	Scientific Literature
8.	ALA4380054	A	Stability in human liver microsomes assessed as parent compound remaining at 5 uM measured after 1 hr in presence of metabolic phase 2 cofactors UDPGA by LC-MS analysis	Homo sapiens	4	ALA4376852	microsome format	Scientific Literature
9.	ALA4380055	A	Stability of the compound in plasma (unknown origin) assessed as parent compound remaining at 5 uM measured after 1 hr by LC-MS analysis	Not specified	4	ALA4376852	cell-free format	Scientific Literature
10.	ALA4380056	A	Protein binding in plasma (unknown origin) at 5 uM measured after 6 hrs by LC-MS based equilibrium dialysis analysis	Not specified	4	ALA4376852	cell-free format	Scientific Literature