| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4386806 | B | Positive allosteric modulation of rat M4 AchR | Rattus norvegicus | 1 | ALA4385625 | single protein format | Scientific Literature | |
| 2. | ALA4386807 | A | Plasma clearance in rat | Rattus norvegicus | 4 | ALA4385625 | assay format | Scientific Literature | |
| 3. | ALA4386808 | A | Permeability coefficient, Kp in rat at 0.2 mg/kg, iv dosed via pBL cassette dosing | Rattus norvegicus | 1 | ALA4385625 | organism-based format | Scientific Literature | |
| 4. | ALA4386809 | A | Unbound brain-to-plasma concentration ratio in rat at 0.2 mg/kg, iv dosed via pBL cassette dosing | Rattus norvegicus | 1 | ALA4385625 | organism-based format | Scientific Literature | |
| 5. | ALA4386810 | A | Permeability coefficient, Kp in rat at 10 mg/kg, ip dosed via pBL cassette dosing | Rattus norvegicus | 1 | ALA4385625 | organism-based format | Scientific Literature | |
| 6. | ALA4386811 | A | Unbound brain-to-plasma concentration ratio in rat at 10 mg/kg, ip dosed via pBL cassette dosing | Rattus norvegicus | 1 | ALA4385625 | organism-based format | Scientific Literature | |
| 7. | ALA4386819 | A | Drug metabolism in rat liver microsomes assessed as AO-mediated metabolite thieno[2,3-c]pyridine-7(6H)-one formation in presence of NADPH by HPLC-UV analysis | Rattus norvegicus | 1 | ALA4385625 | microsome format | Scientific Literature | |
| 8. | ALA4386820 | A | Drug metabolism in rat liver microsomes assessed as AO-mediated metabolite thieno[2,3-c]pyridine-5(6H)-one formation in presence of NADPH by HPLC-UV analysis | Rattus norvegicus | 1 | ALA4385625 | microsome format | Scientific Literature | |
| 9. | ALA4386821 | A | Drug metabolism in rat hepatic S9 fraction assessed as AO-mediated metabolite VU6016365 formation at 25 uM after 1 hr by HPLC-UV analysis | Rattus norvegicus | 1 | ALA4385625 | subcellular format | Scientific Literature | |
| 10. | ALA4386822 | A | Retention time of the compound in rat hepatic S9 fraction at 25 uM after 1 hr in presence of NADPH by HPLC-UV analysis | Rattus norvegicus | 2 | ALA4385625 | subcellular format | Scientific Literature | |
| 11. | ALA4386823 | A | Retention time of the compound in rat hepatic S9 fraction at 25 uM after 1 hr in absence of NADPH by HPLC-UV analysis | Rattus norvegicus | 2 | ALA4385625 | subcellular format | Scientific Literature | |
| 12. | ALA4386824 | A | Drug metabolism in rat hepatic S9 fraction assessed as AO-mediated metabolite VU6016365 formation by mass spectrometry | Rattus norvegicus | 1 | ALA4385625 | subcellular format | Scientific Literature |
The page will load shortly, Thanks for your patience!