# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4392889 | B | Induction of human TLR2/TLR1 heterodimerization expressed in insect Hi5 cells by size exclusion chromatography | Homo sapiens | 2 | ALA4392821 | cell-based format | Scientific Literature | |
2. | ALA4392890 | B | Induction of human TLR2 homodimerization expressed in insect Hi5 cells by size exclusion chromatography | Homo sapiens | 2 | ALA4392821 | cell-based format | Scientific Literature | |
3. | ALA4392894 | B | Agonist activity at human TLR2/TLR1 F312A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 50 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
4. | ALA4392895 | B | Agonist activity at human TLR2/TLR1 Y320A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 50 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
5. | ALA4392896 | B | Agonist activity at human TLR2/TLR1 I319A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 50 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
6. | ALA4392897 | B | Agonist activity at human TLR2/TLR1 W258A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 50 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
7. | ALA4392899 | B | Induction of human TLR1 homodimerization expressed in insect Hi5 cells by size exclusion chromatography | Homo sapiens | 2 | ALA4392821 | cell-based format | Scientific Literature | |
8. | ALA4392900 | B | Agonist activity at human TLR2/TLR1 F314A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 50 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
9. | ALA4392905 | B | Agonist activity at human TLR2/TLR1 V339A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 50 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
10. | ALA4392906 | B | Agonist activity at human TLR2/TLR1 H340A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 50 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
11. | ALA4392907 | B | Agonist activity at human TLR1/TLR2 Y323A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 20 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
12. | ALA4392908 | B | Agonist activity at human TLR1/TLR2 Y325A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 20 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
13. | ALA4392909 | B | Agonist activity at human TLR1/TLR2 V348A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 20 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
14. | ALA4392910 | B | Agonist activity at human TLR1/TLR2 F349A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 20 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
15. | ALA4392911 | B | Agonist activity at human TLR1/TLR2 D327A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 20 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
16. | ALA4392912 | B | Agonist activity at human TLR1/TLR2 L328A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 20 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
17. | ALA4392913 | B | Agonist activity at human TLR1/TLR2 Y332A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 20 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
18. | ALA4392914 | B | Agonist activity at human TLR1/TLR2 L350A mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 20 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature | |
19. | ALA4392915 | B | Agonist activity at human TLR1/TLR2 Y376 mutant expressed in HEK293T cells coexpressing NF-kappaB-driven luciferase reporter at 20 ng/ml after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4392821 | cell-based format | Scientific Literature |