#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4409553	Binding	Inhibition of IFN-gamma-induced human TDO2 transfected in HeLa cells at 10 times IDO1 IC50 concentration using L-tryptophan as substrate incubated for 24 hrs relative to control	Homo sapiens	6	ALA4406863	cell-based format	Scientific Literature
2.	ALA4409557	Binding	Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as increase in IFN-gamma production measured after 48 hrs by ELISA relative to control	Mus musculus	1	ALA4406863	assay format	Scientific Literature
3.	ALA4409558	Binding	Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as increase in T cell proliferation measured after 48 hrs by MTT assay	Mus musculus	3	ALA4406863	assay format	Scientific Literature
4.	ALA4409560	Binding	Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as ConA- stimulated differentiation of Treg cells at 0.3 uM measured after 48 hrs by FOXP3-APC based flow cytometry analysis (Rvb = 11.4 %)	Mus musculus	3	ALA4406863	assay format	Scientific Literature
5.	ALA4409561	Functional	Antitumor activity against mouse CT26 cells xenografted in BALB/c mouse assessed as decrease in tumour growth at 50 mg/kg, po via gavage for 17 days by vernier caliper method	Mus musculus	2	ALA4406863	organism-based format	Scientific Literature
6.	ALA4409562	Functional	Antitumor activity against mouse CT26 cells xenografted in BALB/c mouse assessed as decrease in tumour weight at 50 mg/kg, po via gavage for 17 days by vernier caliper method relative to control	Mus musculus	1	ALA4406863	organism-based format	Scientific Literature
7.	ALA4409563	Toxicity	Toxicity in BALB/c mouse xenografted with mouse CT26 cells assessed as effect on body weight at 50 mg/kg, po via gavage for 17 days and measured at day 17	Mus musculus	1	ALA4406863	organism-based format	Scientific Literature
8.	ALA4409564	Functional	Antitumor activity against mouse CT26 cells xenografted in immunodeficient BALB/c nude mouse assessed as reduction in tumour growth at 50 mg/kg, po via gavage for 10 days by vernier caliper method	Mus musculus	1	ALA4406863	organism-based format	Scientific Literature
9.	ALA4409566	Functional	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells assessed as cell shrinkage at 50 mg/kg via oral gavage for 17 days by H&E staining based analysis	Mus musculus	2	ALA4406863	organism-based format	Scientific Literature
10.	ALA4409567	Functional	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells assessed as nuclear chromatin condensation at 50 mg/kg via oral gavage for 17 days by H&E staining based analysis	Mus musculus	2	ALA4406863	organism-based format	Scientific Literature
11.	ALA4409568	Functional	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells assessed as nuclear chromatin margination at 50 mg/kg via oral gavage for 17 days by H&E staining based analysis	Mus musculus	2	ALA4406863	organism-based format	Scientific Literature
12.	ALA4409569	Functional	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells assessed as decrease in PCNA expression at 50 mg/kg via oral gavage for 17 days by immunohistochemistry analysis	Mus musculus	1	ALA4406863	organism-based format	Scientific Literature
13.	ALA4409570	Functional	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells at 50 mg/kg via oral gavage for 17 days by TUNEL assay	Mus musculus	1	ALA4406863	organism-based format	Scientific Literature
14.	ALA4409571	Functional	Increase in infiltrating CD8-positive T cells in BALB/c mouse xenografted with CT26 cells at 50 mg/kg via oral gavage for 17 day by immunohistochemical analysis	Mus musculus	1	ALA4406863	organism-based format	Scientific Literature
15.	ALA4409572	Functional	Increase in IFN-gamma expression in BALB/c mouse xenografted with CT26 cells at 50 mg/kg via oral gavage for 17 day by immunohistochemical analysis	Mus musculus	1	ALA4406863	organism-based format	Scientific Literature
16.	ALA4409573	Functional	Decrease in FOXP3-postive T cells in BALB/c mouse xenografted with CT26 cells at 50 mg/kg via oral gavage for 17 day by immunohistochemical analysis	Mus musculus	1	ALA4406863	organism-based format	Scientific Literature
17.	ALA4409574	Functional	Increase in Granzyme B expression in BALB/c mouse xenografted with CT26 cells at 50 mg/kg via oral gavage for 17 day by immunohistochemical analysis	Mus musculus	1	ALA4406863	organism-based format	Scientific Literature
18.	ALA4409575	Functional	Effect on IDO1 expression in IFN-gamma-stimulated human HeLa cells at 3 times IDO1 IC50 for 24 hrs by western blot analysis	Homo sapiens	5	ALA4406863	cell-based format	Scientific Literature