| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4307144 | B | Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assay | Homo sapiens | 9 | ALA4304783 | single protein format | Scientific Literature | |
| 2. | ALA4307145 | B | Agonist activity at PPARbeta (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assay | Homo sapiens | 4 | ALA4304783 | single protein format | Scientific Literature | |
| 3. | ALA4307146 | B | Agonist activity at PPARgamma (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assay | Homo sapiens | 4 | ALA4304783 | single protein format | Scientific Literature | |
| 4. | ALA4307147 | B | Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assay relative to GW7647 | Homo sapiens | 8 | ALA4304783 | single protein format | Scientific Literature | |
| 5. | ALA4307148 | B | Agonist activity at PPARbeta (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assay relative to L-165,041 | Homo sapiens | 3 | ALA4304783 | single protein format | Scientific Literature | |
| 6. | ALA4307149 | B | Agonist activity at PPARgamma (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assay relative to Troglitazone | Homo sapiens | 3 | ALA4304783 | single protein format | Scientific Literature | |
| 7. | ALA4307150 | B | Selectivity index, ratio of EC50 of PPARgamma (unknown origin) to EC50 of PPARalpha (unknown origin) | Homo sapiens | 3 | ALA4304783 | assay format | Scientific Literature | |
| 8. | ALA4307151 | B | Selectivity index, ratio of EC50 of PPARgamma (unknown origin) to EC50 of PPARdelta (unknown origin) | Homo sapiens | 3 | ALA4304783 | protein format | Scientific Literature | |
| 9. | ALA4307152 | B | Potency index, ratio of EC50 of GFT505 to ratio of EC50 of compound for agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assay | Homo sapiens | 2 | ALA4304783 | single protein format | Scientific Literature | |
| 10. | ALA4307153 | A | Clearance in human liver microsomes at 1 uM measured upto 60 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA4304783 | microsome format | Scientific Literature | |
| 11. | ALA4307154 | A | Clearance in rat liver microsomes at 1 uM measured upto 60 mins by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA4304783 | microsome format | Scientific Literature | |
| 12. | ALA4307155 | A | Stability in human plasma assessed as remaining compound incubated for 2 hrs | Homo sapiens | 1 | ALA4304783 | cell-free format | Scientific Literature | |
| 13. | ALA4307156 | A | Stability in rat plasma assessed as remaining compound incubated for 2 hrs | Rattus norvegicus | 1 | ALA4304783 | cell-free format | Scientific Literature | |
| 14. | ALA4307157 | A | Protein binding in human plasma at 2 uM incubated for 4 hrs by LC-MS/MS analysis | Homo sapiens | 1 | ALA4304783 | cell-free format | Scientific Literature | |
| 15. | ALA4307158 | A | Protein binding in rat plasma at 2 uM incubated for 4 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA4304783 | cell-free format | Scientific Literature | |
| 16. | ALA4307159 | A | Apparent permeability across apical to basolateral side in human Caco2 cells at 2 uM incubated for 120 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA4304783 | cell-based format | Scientific Literature | |
| 17. | ALA4307160 | A | Apparent permeability across basolateral to apical side in human Caco2 cells at 2 uM incubated for 120 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA4304783 | cell-based format | Scientific Literature | |
| 18. | ALA4307161 | A | Efflux ratio of apparent permeability across basolateral to apical over apical to basolateral side in human Caco2 cells at 2 uM incubated for 120 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA4304783 | cell-based format | Scientific Literature | |
| 19. | ALA4307162 | A | Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 10 mins followed by substrate addition further incubated for 10 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA4304783 | microsome format | Scientific Literature | |
| 20. | ALA4307163 | A | Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 10 mins followed by substrate addition further incubated for 10 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA4304783 | microsome format | Scientific Literature |
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