| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4380405 | F | Antiplasmodial activity against asexual blood stage Plasmodium falciparum 3D7A MR4 infected in human RBCs assessed as decrease in [3H]-hypoxanthine incorporation pretreated for 24 hrs in presence of hypoxanthine followed by [3H]-hypoxanthine addition after 24 hrs by microbeta scintillation counter analysis | Plasmodium falciparum | 5 | organism-based format | Scientific Literature | ||
| 2. | ALA4380407 | B | Binding affinity to Plasmodium falciparum NMT (27 to 410 residues) expressed in Escherichia coli Rosetta (DE3) assessed as change in melting temperature at 100 uM in presence of 100 uM myristoyl-CoA by Sypro orange dye based differential scanning fluorimetry (Rvb = 0 degreeC) | Plasmodium falciparum | 5 | assay format | Scientific Literature | ||
| 3. | ALA4380408 | B | Binding affinity to Plasmodium falciparum NMT (27 to 410 residues) expressed in Escherichia coli Rosetta (DE3) assessed as change in melting temperature at 100 uM in absence of 100 uM myristoyl-CoA by Sypro orange dye based differential scanning fluorimetry (Rvb = 0 degreeC) | Plasmodium falciparum | 5 | assay format | Scientific Literature |
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