#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4380983	A	Agonist activity at C3a receptor in human MDM cells assessed as induction of intracellular calcium release measured at 1 sec interval for => 200 secs by Fluo-3 AM dye-based FLIPR assay	Homo sapiens	28	ALA4376878	cell-based format	Scientific Literature
2.	ALA4380985	F	Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins followed by C3a addition and measured at 1 sec interval for => 200 secs by Fluo-3 AM dye-based FLIPR assay	Homo sapiens	28	ALA4376878	cell-based format	Scientific Literature
3.	ALA4380986	B	Potency index, ratio of SB290157 IC50 to test compound IC50 for antagonist activity at C3a receptor in human MDM cells	Homo sapiens	3	ALA4376878	cell-based format	Scientific Literature
4.	ALA4380988	F	Antagonist activity at C5a receptor in human MDM cells assessed as inhibition of C5a-induced intracellular calcium release preincubated for 30 mins followed by C5a addition and measured at 1 sec interval for => 200 secs by Fluo-3 AM dye-based FLIPR assay	Homo sapiens	4	ALA4376878	cell-based format	Scientific Literature
5.	ALA4380989	A	Stability of the compound in rat plasma at 1 mM measured after 4 hrs by LC-MS analysis	Rattus norvegicus	4	ALA4376878	cell-free format	Scientific Literature
6.	ALA4380992	A	Stability of the compound in rat liver microsomes assessed as compound degradation at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 1 hr by LC-MS/MS analysis	Rattus norvegicus	2	ALA4376878	microsome format	Scientific Literature
7.	ALA4380993	B	Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by C3a addition	Homo sapiens	4	ALA4376878	cell-based format	Scientific Literature
8.	ALA4380994	B	Potency index, ratio of SB290157 IC50 to test compound IC50 for antagonist activity at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release	Homo sapiens	3	ALA4376878	cell-based format	Scientific Literature
9.	ALA4380996	A	AUC (0 to 8 hrs) in Wistar rat at 10 mg/kg, po by LC-MS/MS analysis	Rattus norvegicus	4	ALA4376878	organism-based format	Scientific Literature
10.	ALA4380997	A	Tmax in Wistar rat at 10 mg/kg, po by LC-MS/MS analysis	Rattus norvegicus	4	ALA4376878	organism-based format	Scientific Literature
11.	ALA4380998	A	Cmax in Wistar rat at 10 mg/kg, po by LC-MS/MS analysis	Rattus norvegicus	4	ALA4376878	organism-based format	Scientific Literature
12.	ALA4380999	A	AUC (0 to 8 hrs) in Wistar rat at 1 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	2	ALA4376878	organism-based format	Scientific Literature
13.	ALA4381000	A	Volume of distribution in Wistar rat at 1 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	2	ALA4376878	organism-based format	Scientific Literature
14.	ALA4381001	A	Elimination half-life in Wistar rat at 1 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	2	ALA4376878	organism-based format	Scientific Literature
15.	ALA4381002	A	Clearance in Wistar rat at 1 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	2	ALA4376878	organism-based format	Scientific Literature
16.	ALA4381003	F	Antiinflammatory activity in Wistar rat model of BR103-induced paw edema assessed as reduction in hind paw swelling at 10 mg/kg, po administered via gavage pretreated for 2 hrs followed by BR103 challenge and measured after 30 mins by digital caliper method relative to control	Rattus norvegicus	4	ALA4376878	organism-based format	Scientific Literature